Aguirre Lab

Foy BH, Carlson JCT, Aguirre AD, Higgins JM

Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts.
Nat Commun. 2025;16(1):1113 - PMID: 39875373 - PMCID: PMC11775293 - DOI: 10.1038/s41467-025-56251-9

Roh K, Li H, Freeman RN, Zazzeron L, Lee A, Zhou C, Shen S, Xia P, Guerra JRB, Sheffield C, Padera TP, Zhou Y, Kim S, Aguirre A, Houstis N, Roh JD, Ichinose F, Malhotra R, Rosenzweig A, Rhee J

Exercise-Induced Cardiac Lymphatic Remodeling Mitigates Inflammation in the Aging Heart.
Aging Cell. 2025;24(6):e70043 - PMID: 40083143 - PMCID: PMC12151892 - DOI: 10.1111/acel.70043

Ayers BC, Olverson G, Chukwudi C, Higuita ML, Ajenu E, Bolger-Chen M, Catricala J, Pitti A, Moshe YK, Kang J, Aguirre AD, Sundt TM, Michel E, Osho A, Tessier SN, Alireza Rabi S, D'Alessandro D

Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function.
J Heart Lung Transplant. 2025;:ePub - PMID: 40716473 - DOI: 10.1016/j.healun.2025.07.023

Jaffe AT, Pallarès-López R, Raines JK, Aguirre AD, Anthony BW

Noninvasive Quantitative Compression Ultrasound Central Venous Pressure: A Clinical Pilot Study.
BME Front. 2025;6:0115 - PMID: 40110344 - PMCID: PMC11922486 - DOI: 10.34133/bmef.0115

Ayers BC, Aguirre AD, Sundt TM, Lu MT, Jassar A

An open-source, automated machine learning approach for large-scale image retrieval for thoracic aorta analysis studies.
JAMIA Open. 2025;8(4):ooaf066 - PMID: 40662082 - PMCID: PMC12257624 - DOI: 10.1093/jamiaopen/ooaf066

Kvernebo K, Liv Kristin Wikslund L, Drezek K, Jaramillo A, Capone L, Helmy M, Zhao Y, Aguirre A, D'Alessandro D

COVID-19 Patients Have Peripheral Microvascular Dysfunction and Tissue Hypoxia in Spite of Successful Treatment of Lung Failure: A Proof of Concept Study.
Microcirculation. 2025;32(5):e70014 - PMID: 40598822 - DOI: 10.1111/micc.70014

Haimovich JS, Kolossváry M, Alam R, Padrós-Valls R, Lu MT, Aguirre AD

Risk stratification of chest pain in the emergency department using artificial intelligence applied to electrocardiograms.
Open Heart. 2025;12(2):ePub - PMID: 40889954 - PMCID: PMC12406858 - DOI: 10.1136/openhrt-2025-003343

Xia P, Lee S, Roh K, Griffith J, Zhou Y, Guzman E, Shi Y, Yang Z, Castro C, Li H, Guo YY, Singh A, Knipe RS, Raji I, Xu JH, Babbs RK, Fisher F, Lachey J, Seehra J, Yu PB, Lee SJ, Anderson DG, Aguirre A, Rosenzweig A, Malhotra R, Roh JD

Endothelial ActRIIA inhibition protects the cardiac microvasculature in severe viral respiratory infection.
Res Sq. 2025;:ePub - PMID: 40235477 - PMCID: PMC11998776 - DOI: 10.21203/rs.3.rs-6306417/v1

Palanques-Tost E, Pallarès-López R, Padrós-Valls R, Song S, Reinertsen E, Churchill TW, Stockwell P, Pomerantsev E, Garasic J, Sundt TM, Shah P, Houstis NE, Aguirre AD

Cardiac Output Estimation in the Intensive Care Unit.
JACC Adv. 2025;4(5):101663 - PMID: 40286350 - PMCID: PMC12101535 - DOI: 10.1016/j.jacadv.2025.101663

Koscova Z, Li Q, Robichaux C, Junior VM, Ghanta M, Gupta A, Rosand J, Aguirre A, Hong S, Albert DE, Xue J, Parekh A, Sameni R, Reyna MA, Westover MB, Cliford GD

The Harvard-Emory ECG Database.
medRxiv. 2025;:ePub - PMID: 40385443 - PMCID: PMC12083575 - DOI: 10.1101/2024.09.27.24314503

Li J, Aguirre AD, Moura V, Jin J, Liu C, Zhong L, Sun C, Clifford G, Westover MB, Hong S

An Electrocardiogram Foundation Model Built on over 10 Million Recordings.
NEJM AI. 2025;2(7):ePub - PMID: 40771651 - PMCID: PMC12327759 - DOI: 10.1056/aioa2401033

Akam-Baxter EA, Bergemann D, Ridley SJ, To S, Andrea B, Moon B, Ma H, Zhou Y, Aguirre A, Caravan P, Gonzalez-Rosa JM, Sosnovik DE

Dynamics of collagen oxidation and cross linking in regenerating and irreversibly infarcted myocardium.
Nat Commun. 2024;15(1):4648 - PMID: 38858347 - PMCID: PMC11164919 - DOI: 10.1038/s41467-024-48604-7

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Nat Rev Cardiol. 2024;21(5):348 - PMID: 38110566 - PMCID: PMC11987009 - DOI: 10.1038/s41569-023-00982-z

McCullar KS, Abbaspour S, Wang W, Aguirre AD, Westover MB, Klerman EB

Timing of diuretic administration effects on urine volume in hospitalized patients.
Front Physiol. 2024;14:1208324 - PMID: 38321985 - PMCID: PMC10844419 - DOI: 10.3389/fphys.2023.1208324

Alam R, Aguirre A, Stultz CM

Detecting QT prolongation from a single-lead ECG with deep learning.
PLOS Digit Health. 2024;3(6):e0000539 - PMID: 38917157 - PMCID: PMC11198807 - DOI: 10.1371/journal.pdig.0000539

Ayers BC, Padrós-Valls R, Brownlee S, Steinhorn BS, Shann K, Osho A, Sundt TM, Aguirre AD

Prebypass Critical Closing Pressure Predicts Acute Kidney Injury After Cardiopulmonary Bypass.
J Cardiothorac Vasc Anesth. 2024;39(2):437-446 - PMID: 39645444 - DOI: 10.1053/j.jvca.2024.11.010

Chandrasekhar A, Padrós-Valls R, Pallarès-López R, Palanques-Tost E, Houstis N, Sundt TM, Lee HS, Sodini CG, Aguirre AD

Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit.
Nat Med. 2023;29(8):1998-2006 - PMID: 37550417 - DOI: 10.1038/s41591-023-02474-6

Zeller MWG, Wang C, Keliher EJ, Wojtkiewicz GR, Aguirre A, Maresca K, Su C, Buckbinder L, Wang J, Nahrendorf M, Chen JW

Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction.
Int J Mol Sci. 2023;24(6):ePub - PMID: 36982778 - PMCID: PMC10057533 - DOI: 10.3390/ijms24065704

Akam EA, Bergemann D, Ridley SJ, To S, Andrea B, Moon B, Ma H, Zhou Y, Aguirre A, Caravan P, Gonzalez-Rosa JM, Sosnovik DE

Dynamics of Collagen Oxidation and Cross Linking in Regenerating and Irreversibly Infarcted Myocardium.
bioRxiv. 2023;:ePub - PMID: 37546963 - PMCID: PMC10402057 - DOI: 10.1101/2023.07.25.549713

Alam R, Aguirre AD, Stultz CM

QTNet: Deep Learning for Estimating QT Intervals Using a Single Lead ECG.
Annu Int Conf IEEE Eng Med Biol Soc. 2023;2023:1-4 - PMID: 38261472 - DOI: 10.1109/EMBC40787.2023.10341204

Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM

Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations.
Nat Commun. 2022;13(1):4705 - PMID: 35995789 - PMCID: PMC9395541 - DOI: 10.1038/s41467-022-32222-2

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Nat Rev Cardiol. 2022;19(10):684-703 - PMID: 35449407 - PMCID: PMC9982688 - DOI: 10.1038/s41569-022-00687-9

Diamant N, Reinertsen E, Song S, Aguirre AD, Stultz CM, Batra P

Patient contrastive learning: A performant, expressive, and practical approach to electrocardiogram modeling.
PLoS Comput Biol. 2022;18(2):e1009862 - PMID: 35157695 - PMCID: PMC8880931 - DOI: 10.1371/journal.pcbi.1009862

Raghu VK, Moonsamy P, Sundt TM, Ong CS, Singh S, Cheng A, Hou M, Denning L, Gleason TG, Aguirre AD, Lu MT

Deep Learning to Predict Mortality After Cardiothoracic Surgery Using Preoperative Chest Radiographs.
Ann Thorac Surg. 2022;115(1):257-264 - PMID: 35609650 - PMCID: PMC11373441 - DOI: 10.1016/j.athoracsur.2022.04.056

Aguirre AD, Shelton KT

Remote monitoring in the use of extracorporeal membrane oxygenation and acute mechanical circulatory support.
Curr Opin Crit Care. 2022;28(3):308-314 - PMID: 35653252 - DOI: 10.1097/MCC.0000000000000949

Wissmeyer G, Kassab MB, Kawamura Y, Aguirre AD, Jaffer FA

Intravital Microscopy in Atherosclerosis Research.
Methods Mol Biol. 2022;2419:645-658 - PMID: 35237994 - PMCID: PMC9052099 - DOI: 10.1007/978-1-0716-1924-7_40

Grune J, Lewis AJM, Yamazoe M, Hulsmans M, Rohde D, Xiao L, Zhang S, Ott C, Calcagno DM, Zhou Y, Timm K, Shanmuganathan M, Pulous FE, Schloss MJ, Foy BH, Capen D, Vinegoni C, Wojtkiewicz GR, Iwamoto Y, Grune T, Brown D, Higgins J, Ferreira VM, Herring N, Channon KM, Neubauer S, Oxford Acute Myocardial Infarction (OxAMI) Study, Sosnovik DE, Milan DJ, Swirski FK, King KR, Aguirre AD, Ellinor PT, Nahrendorf M

Neutrophils incite and macrophages avert electrical storm after myocardial infarction.
Nat Cardiovasc Res. 2022;1(7):649-664 - PMID: 36034743 - PMCID: PMC9410341 - DOI: 10.1038/s44161-022-00094-w

Aguirre AD, Arbab-Zadeh A, Soeda T, Fuster V, Jang IK

Optical Coherence Tomography of Plaque Vulnerability and Rupture: JACC Focus Seminar Part 1/3.
J Am Coll Cardiol. 2021;78(12):1257-1265 - PMID: 34531027 - PMCID: PMC9851427 - DOI: 10.1016/j.jacc.2021.06.050

Calcagno DM, Zhang C, Toomu A, Huang K, Ninh VK, Miyamoto S, Aguirre AD, Fu Z, Heller Brown J, King KR

SiglecF(HI) Marks Late-Stage Neutrophils of the Infarcted Heart: A Single-Cell Transcriptomic Analysis of Neutrophil Diversification.
J Am Heart Assoc. 2021;10(4):e019019 - PMID: 33525909 - PMCID: PMC7955351 - DOI: 10.1161/JAHA.120.019019

Ong CS, Reinertsen E, Sun H, Moonsamy P, Mohan N, Funamoto M, Kaneko T, Shekar PS, Schena S, Lawton JS, D'Alessandro DA, Westover MB, Aguirre AD, Sundt TM

Prediction of operative mortality for patients undergoing cardiac surgical procedures without established risk scores.
J Thorac Cardiovasc Surg. 2021;165(4):1449-1459.e15 - PMID: 34607725 - PMCID: PMC8918430 - DOI: 10.1016/j.jtcvs.2021.09.010

Ong CS, Reinertsen E, Moonsamy P, Young K, Song S, Axtell AL, Wolfe SB, Mohan N, Jassar AS, Aguirre AD, Sundt TM

Late onset atrial fibrillation in patients undergoing surgical aortic valve replacement.
J Card Surg. 2021;37(2):285-289 - PMID: 34699088 - DOI: 10.1111/jocs.16093

Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM

White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery.
medRxiv. 2021;:ePub - PMID: 34189534 - PMCID: PMC8240689 - DOI: 10.1101/2021.06.19.21259181

Calcagno DM, Ng RP, Toomu A, Zhang C, Huang K, Aguirre AD, Weissleder R, Daniels LB, Fu Z, King KR

The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages.
Sci Immunol. 2020;5(51):ePub - PMID: 32978242 - PMCID: PMC7808338 - DOI: 10.1126/sciimmunol.aaz1974

Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, Robson PM, Soultanidis G, Pérez-Medina C, Teunissen AJP, Toner YC, Ishikawa K, Fish K, Sakurai K, van Leeuwen EM, Klein ED, Sofias AM, Reiner T, Rohde D, Aguirre AD, Wojtkiewicz G, Schmidt S, Iwamoto Y, Izquierdo-Garcia D, Caravan P, Swirski FK, Weissleder R, Mulder WJM

Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs.
Circ Cardiovasc Imaging. 2020;13(10):e010586 - PMID: 33076700 - PMCID: PMC7583675 - DOI: 10.1161/CIRCIMAGING.120.010586

Foy BH, Carlson JCT, Reinertsen E, Padros I Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM

Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection.
JAMA Netw Open. 2020;3(9):e2022058 - PMID: 32965501 - PMCID: PMC7512057 - DOI: 10.1001/jamanetworkopen.2020.22058

Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.
Proc Natl Acad Sci U S A. 2019;116(24):11966-11971 - PMID: 31123149 - PMCID: PMC6575581 - DOI: 10.1073/pnas.1818434116

Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre AD, Nahrendorf M, Weissleder R

A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart.
Bioconjug Chem. 2019;30(3):733-740 - PMID: 30615425 - PMCID: PMC6483069 - DOI: 10.1021/acs.bioconjchem.8b00882

Hulsmans M, Aguirre AD, Bonner MD, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M

A Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse.
Circ Res. 2018;123(11):1208-1219 - PMID: 30571465 - PMCID: PMC6309285 - DOI: 10.1161/CIRCRESAHA.118.313429

King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R

IRF3 and type I interferons fuel a fatal response to myocardial infarction.
Nat Med. 2017;23(12):1481-1487 - PMID: 29106401 - PMCID: PMC6477926 - DOI: 10.1038/nm.4428

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M

Macrophages Facilitate Electrical Conduction in the Heart.
Cell. 2017;169(3):510-522.e20 - PMID: 28431249 - PMCID: PMC5474950 - DOI: 10.1016/j.cell.2017.03.050

Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK

Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.
J Am Coll Cardiol. 2017;69(20):2502-2513 - PMID: 28521888 - DOI: 10.1016/j.jacc.2017.03.556

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Nat Commun. 2017;8:14064 - PMID: 28091604 - PMCID: PMC5241815 - DOI: 10.1038/ncomms14064

Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK

Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study.
J Am Heart Assoc. 2017;6(11):ePub - PMID: 29092845 - PMCID: PMC5721742 - DOI: 10.1161/JAHA.117.006241

Aguirre AD, Apiou-Sbirlea G, Roblyer D, Tromberg BJ

Special Section Guest Editorial: Translational Biophotonics.
J Biomed Opt. 2017;22(12):1-2 - PMID: 29282907 - DOI: 10.1117/1.JBO.22.12.121601

Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK

Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography.
Coron Artery Dis. 2017;28(7):557-563 - PMID: 28704243 - DOI: 10.1097/MCA.0000000000000534

Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK

Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study.
Arterioscler Thromb Vasc Biol. 2016;36(11):2229-2238 - PMID: 27634834 - DOI: 10.1161/ATVBAHA.116.307891

Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK

Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study.
Coron Artery Dis. 2016;27(5):350-6 - PMID: 27105047 - PMCID: PMC4912393 - DOI: 10.1097/MCA.0000000000000370

Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK

Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents.
Coron Artery Dis. 2016;27(1):19-28 - PMID: 26554662 - PMCID: PMC4679565 - DOI: 10.1097/MCA.0000000000000319

Vinegoni C, Aguirre AD, Lee S, Weissleder R

Imaging the beating heart in the mouse using intravital microscopy techniques.
Nat Protoc. 2015;10(11):1802-19 - PMID: 26492138 - PMCID: PMC5380003 - DOI: 10.1038/nprot.2015.119

Minami Y, Ong DS, Uemura S, Wang Z, Aguirre AD, Mukhopadhyay S, Soeda T, Vergallo R, Jia H, Tian J, Hu S, Kim SJ, Park CB, Dauerman HL, Lee S, Jang IK

Impacts of lesion angle on incidence and distribution of acute vessel wall injuries and strut malapposition after drug-eluting stent implantation assessed by optical coherence tomography.
Eur Heart J Cardiovasc Imaging. 2015;16(12):1390-8 - PMID: 25925215 - DOI: 10.1093/ehjci/jev108

Vinegoni C, Lee S, Aguirre AD, Weissleder R

New techniques for motion-artifact-free in vivo cardiac microscopy.
Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079 - DOI: 10.3389/fphys.2015.00147

Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK

Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome.
Thromb Haemost. 2015;115(2):237-9 - PMID: 26423215 - DOI: 10.1160/TH15-05-0412

Aguirre AD, Vinegoni C, Sebas M, Weissleder R

Intravital imaging of cardiac function at the single-cell level.
Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110 - DOI: 10.1073/pnas.1401316111

Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H, Weissleder R

Magnetic ligation method for quantitative detection of microRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672

Wang Z, Jia H, Tian J, Soeda T, Vergallo R, Minami Y, Lee H, Aguirre A, Fujimoto JG, Jang IK

Computer-aided image analysis algorithm to enhance in vivo diagnosis of plaque erosion by intravascular optical coherence tomography.
Circ Cardiovasc Imaging. 2014;7(5):805-10 - PMID: 25034595 - DOI: 10.1161/CIRCIMAGING.114.002084

Hiremath P, Bauer M, Aguirre AD, Cheng HW, Unno K, Patel RB, Harvey BW, Chang WT, Groarke JD, Liao R, Cheng S

Identifying early changes in myocardial microstructure in hypertensive heart disease.
PLoS One. 2014;9(5):e97424 - PMID: 24831515 - PMCID: PMC4022613 - DOI: 10.1371/journal.pone.0097424

Hu S, Yonetsu T, Jia H, Karanasos A, Aguirre AD, Tian J, Abtahian F, Vergallo R, Soeda T, Lee H, McNulty I, Kato K, Yu B, Mizuno K, Toutouzas K, Stefanadis C, Jang IK

Residual thrombus pattern in patients with ST-segment elevation myocardial infarction caused by plaque erosion versus plaque rupture after successful fibrinolysis: an optical coherence tomography study.
J Am Coll Cardiol. 2013;63(13):1336-1338 - PMID: 24361315 - DOI: 10.1016/j.jacc.2013.11.025

Jia H, Abtahian F, Aguirre AD, Lee S, Chia S, Lowe H, Kato K, Yonetsu T, Vergallo R, Hu S, Tian J, Lee H, Park SJ, Jang YS, Raffel OC, Mizuno K, Uemura S, Itoh T, Kakuta T, Choi SY, Dauerman HL, Prasad A, Toma C, McNulty I, Zhang S, Yu B, Fuster V, Narula J, Virmani R, Jang IK

In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography.
J Am Coll Cardiol. 2013;62(19):1748-58 - PMID: 23810884 - PMCID: PMC3874870 - DOI: 10.1016/j.jacc.2013.05.071

Vergallo R, Ren X, Yonetsu T, Kato K, Uemura S, Yu B, Jia H, Abtahian F, Aguirre AD, Tian J, Hu S, Soeda T, Lee H, McNulty I, Park SJ, Jang Y, Prasad A, Lee S, Zhang S, Porto I, Biasucci LM, Crea F, Jang IK

Pancoronary plaque vulnerability in patients with acute coronary syndrome and ruptured culprit plaque: a 3-vessel optical coherence tomography study.
Am Heart J. 2013;167(1):59-67 - PMID: 24332143 - DOI: 10.1016/j.ahj.2013.10.011

Lee HC, Liu JJ, Sheikine Y, Aguirre AD, Connolly JL, Fujimoto JG

Ultrahigh speed spectral-domain optical coherence microscopy.
Biomed Opt Express. 2013;4(8):1236-54 - PMID: 24009989 - PMCID: PMC3756571 - DOI: 10.1364/BOE.4.001236

Lee HC, Zhou C, Cohen DW, Mondelblatt AE, Wang Y, Aguirre AD, Shen D, Sheikine Y, Fujimoto JG, Connolly JL

Integrated optical coherence tomography and optical coherence microscopy imaging of ex vivo human renal tissues.
J Urol. 2011;187(2):691-9 - PMID: 22177199 - PMCID: PMC3366589 - DOI: 10.1016/j.juro.2011.09.149

Zhou C, Cohen DW, Wang Y, Lee HC, Mondelblatt AE, Tsai TH, Aguirre AD, Fujimoto JG, Connolly JL

Integrated optical coherence tomography and microscopy for ex vivo multiscale evaluation of human breast tissues.
Cancer Res. 2010;70(24):10071-9 - PMID: 21056988 - PMCID: PMC3028517 - DOI: 10.1158/0008-5472.CAN-10-2968

Aguirre AD, Sawinski J, Huang SW, Zhou C, Denk W, Fujimoto JG

High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe.
Opt Express. 2010;18(5):4222-39 - PMID: 20389435 - PMCID: PMC2908909 - DOI: 10.1364/OE.18.004222

Zhou C, Wang Y, Aguirre AD, Tsai TH, Cohen DW, Connolly JL, Fujimoto JG

Ex vivo imaging of human thyroid pathology using integrated optical coherence tomography and optical coherence microscopy.
J Biomed Opt. 2010;15(1):016001 - PMID: 20210448 - PMCID: PMC2844129 - DOI: 10.1117/1.3306696

Aguirre AD, Chen Y, Bryan B, Mashimo H, Huang Q, Connolly JL, Fujimoto JG

Cellular resolution ex vivo imaging of gastrointestinal tissues with optical coherence microscopy.
J Biomed Opt. 2010;15(1):016025 - PMID: 20210470 - PMCID: PMC2847935 - DOI: 10.1117/1.3322704

Chen Y, Aguirre AD, Hsiung PL, Huang SW, Mashimo H, Schmitt JM, Fujimoto JG

Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues.
Opt Express. 2008;16(4):2469-85 - PMID: 18542326 - DOI: 10.1364/oe.16.002469

Chen Y, Aguirre AD, Ruvinskaya L, Devor A, Boas DA, Fujimoto JG

Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation.
J Neurosci Methods. 2008;178(1):162-73 - PMID: 19121336 - PMCID: PMC3004397 - DOI: 10.1016/j.jneumeth.2008.11.026

Hsiung PL, Phatak DR, Chen Y, Aguirre AD, Fujimoto JG, Connolly JL

Benign and malignant lesions in the human breast depicted with ultrahigh resolution and three-dimensional optical coherence tomography.
Radiology. 2007;244(3):865-74 - PMID: 17630358 - DOI: 10.1148/radiol.2443061536

Aguirre AD, Hertz PR, Chen Y, Fujimoto JG, Piyawattanametha W, Fan L, Wu MC

Two-axis MEMS Scanning Catheter for Ultrahigh Resolution Three-dimensional and En Face Imaging.
Opt Express. 2007;15(5):2445-53 - PMID: 19532481 - DOI: 10.1364/oe.15.002445

Huang SW, Aguirre AD, Huber RA, Adler DC, Fujimoto JG

Swept source optical coherence microscopy using a Fourier domain mode-locked laser.
Opt Express. 2007;15(10):6210-7 - PMID: 19546926 - DOI: 10.1364/oe.15.006210

Chen Y, Huang SW, Aguirre AD, Fujimoto JG

High-resolution line-scanning optical coherence microscopy.
Opt Lett. 2007;32(14):1971-3 - PMID: 17632613 - DOI: 10.1364/ol.32.001971

Chen Y, Andrews PM, Aguirre AD, Schmitt JM, Fujimoto JG

High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo.
J Biomed Opt. 2007;12(3):034008 - PMID: 17614716 - DOI: 10.1117/1.2736421

Aguirre A, Nishizawa N, Fujimoto J, Seitz W, Lederer M, Kopf D

Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm.
Opt Express. 2006;14(3):1145-60 - PMID: 19503436 - DOI: 10.1364/oe.14.001145

Hsiung PL, Pantanowitz L, Aguirre AD, Chen Y, Phatak D, Ko TH, Bourquin S, Schnitt SJ, Raza S, Connolly JL, Mashimo H, Fujimoto JG

Ultrahigh-resolution and 3-dimensional optical coherence tomography ex vivo imaging of the large and small intestines.
Gastrointest Endosc. 2005;62(4):561-74 - PMID: 16185971 - DOI: 10.1016/j.gie.2005.05.006

Herz P, Chen Y, Aguirre A, Fujimoto J, Mashimo H, Schmitt J, Koski A, Goodnow J, Petersen C

Ultrahigh resolution optical biopsy with endoscopic optical coherence tomography.
Opt Express. 2004;12(15):3532-42 - PMID: 19483882 - DOI: 10.1364/opex.12.003532

Aguirre AD, Hsiung P, Ko TH, Hartl I, Fujimoto JG

High-resolution optical coherence microscopy for high-speed, in vivo cellular imaging.
Opt Lett. 2003;28(21):2064-6 - PMID: 14587816 - DOI: 10.1364/ol.28.002064
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