Wellman Center Discovery Pipeline

Massachusetts General Hospital / Harvard Medical School

Discoveries in Clinical Use Today- (FDA approved or cleared)

  • Normalization of Scars by Fractionated Laser Treatment
  • Burns-Smart laser surgery
  • Skin Assessment by Confocal Microscopy
  • Pseudofolliculitis Barbae Treatment - Inflammatory disease of hair follicles
  • Rapid Eye Assessment by OCT
  • Wet Macular Degeneration - Visudyne - Novartis
  • Glaucoma Treatment - Laser Trabeculoplasty
  • Improvement of Wound Healing by Low-Level Light Therapy
  • Kidney Stones Laser Lithotripsy
  • Tattoo Removal (requested by DOD)
  • Hair Removal (requested by DOD)
  • Vascular Abnormalities Treatment - birth marks, port wine stains, spider veins
  • Cardiac Interventions -visualization of coronary arteries in real time
  • Gastroenterology (GI) Interventions -visualization of the total GI track in real time (3)
  • Noninvasive Fat Removal - Zeltiq
  • Vocal Cord Treatment: polyps, cancer
  • Resurfacing of Aging Skin
  • Treatment of pigmentary lesions on the skin
  • Treatment of skin cancers
  • Image-guided biopsy of Early Cancer
  • Fractionated Epidermal Grafting for Wounds
  • Tissue Copying device for full thickness skin grafting
  • Tissue Copying for Wounds
  • Treatment for Vitiligo
  • Diagnosis of Eosinophilic Esophagitis
  • Wound and burn autologous full thickness skin grafting at bedside

Platform Technologies Developed or Advanced by Wellman

  • Fractional Laser Therapy
  • Non-Invasive Imaging
    • Confocal Microscopy
    • Optical Coherence Tomography (OCT)
    • Broadband Diffuse Optical Spectroscopy
    • Modulated (Hyperspectral) Imaging
  • Photochemical Tissue Bonding (PTB)
  • Photodynamic Therapy (PDT)
  • Selective Photothermolysis
  • Tissue copying for multiple applications
  • Smart bandages
  • Intra-vascular Imaging & Catheters
  • Micro OCT
    • Oral Capsule Micro Imaging
    • Whole Organ Micro ImagingIll. Cancer Smart Bombs
  • Cryolipolysis
  • Human Performance Enchancement
  • Injury Prevention and Monitoring
  • Coagulopathy Detection System
  • Acoustic Radiative Force Technology (AR Force)
  • FLIM Imaging