Aguirre Lab

Foy BH, Carlson JCT, Aguirre AD, Higgins JM

Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts.
Nat Commun. 2025;16(1):1113 - PMID: 39875373 - PMCID: PMC11775293 - DOI: 10.1038/s41467-025-56251-9

Roh K, Li H, Freeman RN, Zazzeron L, Lee A, Zhou C, Shen S, Xia P, Guerra JRB, Sheffield C, Padera TP, Zhou Y, Kim S, Aguirre A, Houstis N, Roh JD, Ichinose F, Malhotra R, Rosenzweig A, Rhee J

Exercise-Induced Cardiac Lymphatic Remodeling Mitigates Inflammation in the Aging Heart.
Aging Cell. 2025;24(6):e70043 - PMID: 40083143 - PMCID: PMC12151892 - DOI: 10.1111/acel.70043

Ayers BC, Olverson G, Chukwudi C, Higuita ML, Ajenu E, Bolger-Chen M, Catricala J, Pitti A, Moshe YK, Kang J, Aguirre AD, Sundt TM, Michel E, Osho A, Tessier SN, Alireza Rabi S, D'Alessandro D

Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function.
J Heart Lung Transplant. 2025;:ePub - PMID: 40716473 - DOI: 10.1016/j.healun.2025.07.023

Jaffe AT, Pallarès-López R, Raines JK, Aguirre AD, Anthony BW

Noninvasive Quantitative Compression Ultrasound Central Venous Pressure: A Clinical Pilot Study.
BME Front. 2025;6:0115 - PMID: 40110344 - PMCID: PMC11922486 - DOI: 10.34133/bmef.0115

Ayers BC, Aguirre AD, Sundt TM, Lu MT, Jassar A

An open-source, automated machine learning approach for large-scale image retrieval for thoracic aorta analysis studies.
JAMIA Open. 2025;8(4):ooaf066 - PMID: 40662082 - PMCID: PMC12257624 - DOI: 10.1093/jamiaopen/ooaf066

Kvernebo K, Liv Kristin Wikslund L, Drezek K, Jaramillo A, Capone L, Helmy M, Zhao Y, Aguirre A, D'Alessandro D

COVID-19 Patients Have Peripheral Microvascular Dysfunction and Tissue Hypoxia in Spite of Successful Treatment of Lung Failure: A Proof of Concept Study.
Microcirculation. 2025;32(5):e70014 - PMID: 40598822 - DOI: 10.1111/micc.70014

Haimovich JS, Kolossváry M, Alam R, Padrós-Valls R, Lu MT, Aguirre AD

Risk stratification of chest pain in the emergency department using artificial intelligence applied to electrocardiograms.
Open Heart. 2025;12(2):ePub - PMID: 40889954 - PMCID: PMC12406858 - DOI: 10.1136/openhrt-2025-003343

Xia P, Lee S, Roh K, Griffith J, Zhou Y, Guzman E, Shi Y, Yang Z, Castro C, Li H, Guo YY, Singh A, Knipe RS, Raji I, Xu JH, Babbs RK, Fisher F, Lachey J, Seehra J, Yu PB, Lee SJ, Anderson DG, Aguirre A, Rosenzweig A, Malhotra R, Roh JD

Endothelial ActRIIA inhibition protects the cardiac microvasculature in severe viral respiratory infection.
Res Sq. 2025;:ePub - PMID: 40235477 - PMCID: PMC11998776 - DOI: 10.21203/rs.3.rs-6306417/v1

Palanques-Tost E, Pallarès-López R, Padrós-Valls R, Song S, Reinertsen E, Churchill TW, Stockwell P, Pomerantsev E, Garasic J, Sundt TM, Shah P, Houstis NE, Aguirre AD

Cardiac Output Estimation in the Intensive Care Unit.
JACC Adv. 2025;4(5):101663 - PMID: 40286350 - PMCID: PMC12101535 - DOI: 10.1016/j.jacadv.2025.101663

Koscova Z, Li Q, Robichaux C, Junior VM, Ghanta M, Gupta A, Rosand J, Aguirre A, Hong S, Albert DE, Xue J, Parekh A, Sameni R, Reyna MA, Westover MB, Cliford GD

The Harvard-Emory ECG Database.
medRxiv. 2025;:ePub - PMID: 40385443 - PMCID: PMC12083575 - DOI: 10.1101/2024.09.27.24314503

Li J, Aguirre AD, Moura V, Jin J, Liu C, Zhong L, Sun C, Clifford G, Westover MB, Hong S

An Electrocardiogram Foundation Model Built on over 10 Million Recordings.
NEJM AI. 2025;2(7):ePub - PMID: 40771651 - PMCID: PMC12327759 - DOI: 10.1056/aioa2401033
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