Lin Lab

Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D

Resilient anatomy and local plasticity of naive and stress haematopoiesis.
Nature. 2024;627(8005):839-846 - PMID: 38509363 - PMCID: PMC10972750 - DOI: 10.1038/s41586-024-07186-6

Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K

A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate.
Cell Stem Cell. 2024;31(3):359-377.e10 - PMID: 38458178 - PMCID: PMC10957094 - DOI: 10.1016/j.stem.2024.02.004

Conedera FM, Kokona D, Zinkernagel MS, Stein JV, Lin CP, Alt C, Enzmann V

Macrophages coordinate immune response to laser-induced injury via extracellular traps.
J Neuroinflammation. 2024;21(1):68 - PMID: 38500151 - PMCID: PMC10949579 - DOI: 10.1186/s12974-024-03064-0

Turcotte R, Wu JW, Lin CP

Intravital multiphoton photoconversion with a cell membrane dye.
J Biophotonics. 2016;10(2):206-210 - PMID: 27433967 - DOI: 10.1002/jbio.201600077

Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M

Continuous volumetric imaging via an optical phase-locked ultrasound lens.
Nat Methods. 2015;12(8):759-62 - PMID: 26167641 - PMCID: PMC4551496 - DOI: 10.1038/nmeth.3476

Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA

Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S

Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
Cell. 2014;158(5):1110-1122 - PMID: 25171411 - PMCID: PMC4149753 - DOI: 10.1016/j.cell.2014.07.013

Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT

Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426

Roussakis E, Spencer JA, Lin CP, Vinogradov SA

Two-photon antenna-core oxygen probe with enhanced performance.
Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907 - DOI: 10.1021/ac501028m

Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin CP

In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment.
Invest Ophthalmol Vis Sci. 2014;55(8):5314-9 - PMID: 25082884 - DOI: 10.1167/iovs.14-14254

Turcotte R, Alt C, Mortensen LJ, Lin CP

Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy.
Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326 - DOI: 10.1364/BOE.5.003578

Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP

Femtosecond laser bone ablation with a high repetition rate fiber laser source.
Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121 - DOI: 10.1364/BOE.6.000032

Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA

Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017

Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP

Cell labeling approaches for fluorescence-based in vivo flow cytometry.
Cytometry A. 2011;79(10):758-65 - PMID: 21905206 - PMCID: PMC3686107 - DOI: 10.1002/cyto.a.21125

Kim P, Puoris'haag M, Côté D, Lin CP, Yun SH

In vivo confocal and multiphoton microendoscopy.
J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311 - DOI: 10.1117/1.2839043

Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam.
Invest Ophthalmol Vis Sci. 2007;48(4):1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797

Alt C, Veilleux I, Lee H, Pitsillides CM, Côté D, Lin CP

Retinal flow cytometer.
Opt Lett. 2007;32(23):3450-2 - PMID: 18059963 - PMCID: PMC2794483 - DOI: 10.1364/ol.32.003450

Evans CL, Potma EO, Puoris'haag M, Côté D, Lin CP, Xie XS

Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
Proc Natl Acad Sci U S A. 2005;102(46):16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102

Pitsillides CM, Joe EK, Wei X, Anderson RR, Lin CP

Selective cell targeting with light-absorbing microparticles and nanoparticles.
Biophys J. 2003;84(6):4023-32 - PMID: 12770906 - PMCID: PMC1302982 - DOI: 10.1016/S0006-3495(03)75128-5

Wei X, Runnels JM, Lin CP

Selective uptake of indocyanine green by reticulocytes in circulation.
Invest Ophthalmol Vis Sci. 2003;44(10):4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041

Bogdanov AA, Lin CP, Simonova M, Matuszewski L, Weissleder R

Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment.
Neoplasia. 2002;4(3):228-36 - PMID: 11988842 - PMCID: PMC1531696 - DOI: 10.1038/sj.neo.7900238
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