Hasan Lab

Obaid G, Bano S, Mallidi S, Broekgaarden M, Kuriakose J, Silber Z, Bulin AL, Wang Y, Mai Z, Jin W, Simeone D, Hasan T

Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates: Towards Conquering Desmoplasia?
Nano Lett. 2019;19(11):7573-7587 - PMID: 31518145 - PMCID: PMC6934365 - DOI: 10.1021/acs.nanolett.9b00859

Broekgaarden M, Anbil S, Bulin AL, Obaid G, Mai Z, Baglo Y, Rizvi I, Hasan T

Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer.
Biomaterials. 2019;222:119421 - PMID: 31494503 - PMCID: PMC6934357 - DOI: 10.1016/j.biomaterials.2019.119421

Nath S, Saad MA, Pigula M, Swain JWR, Hasan T

Photoimmunotherapy of Ovarian Cancer: A Unique Niche in the Management of Advanced Disease.
Cancers (Basel). 2019;11(12):ePub - PMID: 31783651 - PMCID: PMC6966499 - DOI: 10.3390/cancers11121887

Mallidi S, Khan AP, Liu H, Daly L, Rudd G, Leon P, Khan S, Hussain BMA, Hasan SA, Siddique SA, Akhtar K, August M, Troulis M, Cuckov F, Celli JP, Hasan T

Platform for ergonomic intraoral photodynamic therapy using low-cost, modular 3D-printed components: Design, comfort and clinical evaluation.
Sci Rep. 2019;9(1):15830 - PMID: 31676807 - PMCID: PMC6825190 - DOI: 10.1038/s41598-019-51859-6

Woodward RI, Majewski MR, Macadam N, Hu G, Albrow-Owen T, Hasan T, Jackson SD

Q-switched Dy:ZBLAN fiber lasers beyond 3 μm: comparison of pulse generation using acousto-optic modulation and inkjet-printed black phosphorus.
Opt Express. 2019;27(10):15032-15045 - PMID: 31163942 - DOI: 10.1364/OE.27.015032

Lu J, Roy B, Anderson M, Leggett CL, Levy MJ, Pogue B, Hasan T, Wang KK

Verteporfin- and sodium porfimer-mediated photodynamic therapy enhances pancreatic cancer cell death without activating stromal cells in the microenvironment.
J Biomed Opt. 2019;24(11):1-11 - PMID: 31741351 - PMCID: PMC7003148 - DOI: 10.1117/1.JBO.24.11.118001

Ruiz AJ, LaRochelle EPM, Gunn JR, Hull SM, Hasan T, Chapman MS, Pogue BW

Smartphone fluorescence imager for quantitative dosimetry of protoporphyrin-IX-based photodynamic therapy in skin.
J Biomed Opt. 2019;25(6):1-13 - PMID: 31820594 - PMCID: PMC6901011 - DOI: 10.1117/1.JBO.25.6.063802

Spring BQ, Lang RT, Kercher EM, Rizvi I, Wenham RM, Conejo-Garcia JR, Hasan T, Gatenby RA, Enderling H

Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies.
Front Phys. 2019;7:ePub - PMID: 31123672 - PMCID: PMC6529192 - DOI: 10.3389/fphy.2019.00046

Rizvi I, Nath S, Obaid G, Ruhi MK, Moore K, Bano S, Kessel D, Hasan T

A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer.
Photochem Photobiol. 2019;95(1):419-429 - PMID: 30499113 - PMCID: PMC7473467 - DOI: 10.1111/php.13066

Nath S, Obaid G, Hasan T

The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire.
Photochem Photobiol. 2019;95(6):1288-1305 - PMID: 31602649 - PMCID: PMC6878142 - DOI: 10.1111/php.13173

Bulin AL, Broekgaarden M, Simeone D, Hasan T

Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids.
Oncotarget. 2019;10(27):2625-2643 - PMID: 31080554 - PMCID: PMC6499000 - DOI: 10.18632/oncotarget.26780

Broekgaarden M, Bulin AL, Frederick J, Mai Z, Hasan T

Tracking Photodynamic- and Chemotherapy-Induced Redox-State Perturbations in 3D Culture Models of Pancreatic Cancer: A Tool for Identifying Therapy-Induced Metabolic Changes.
J Clin Med. 2019;8(9):ePub - PMID: 31500115 - PMCID: PMC6788194 - DOI: 10.3390/jcm8091399

LaRochelle EPM, Chapman MS, Maytin EV, Hasan T, Pogue BW

Weather-informed Light-tissue Model-Based Dose Planning for Indoor Daylight Photodynamic Therapy.
Photochem Photobiol. 2019;96(2):320-326 - PMID: 31581341 - PMCID: PMC7117968 - DOI: 10.1111/php.13170

Fisher C, Obaid G, Niu C, Foltz W, Goldstein A, Hasan T, Lilge L

Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma.
J Clin Med. 2019;8(12):ePub - PMID: 31847378 - PMCID: PMC6947404 - DOI: 10.3390/jcm8122214
14