Tsao Lab

Kong EL, Sullivan R, Tsao H, Chen ST

Geographic Variation in the Impact of Novel Melanoma Therapies on Mortality.
J Am Acad Dermatol. 2026;:ePub - PMID: 41812981 - DOI: 10.1016/j.jaad.2026.03.012

Kumar R, Calderon Alonso AI, Ji Z, Njauw CN, Kumar S, Tsao H

Differential stability of NRAS and BRAF oncoproteins in melanoma.
J Invest Dermatol. 2026;:ePub - PMID: 41763640 - DOI: 10.1016/j.jid.2026.02.009

Kaveti A, Sullivan RJ, Tsao H

KIT-Mutant Melanoma: Understanding the Pathway to Personalized Therapy.
Cancers (Basel). 2025;17(22):ePub - PMID: 41301010 - PMCID: PMC12650433 - DOI: 10.3390/cancers17223644

Rashid S, Usoltsev D, Gupta S, Artomov M, Tsao H

Mendelian randomization analysis provides insights into the relationship between inflammatory bowel disease and skin cancer.
Mol Clin Oncol. 2025;23(3):83 - PMID: 40718635 - PMCID: PMC12290388 - DOI: 10.3892/mco.2025.2878

Latoni DI, Kim SH, Tsao H

Systemic Therapies for Metastatic Melanoma.
Dermatol Clin. 2025;43(3):483-494 - PMID: 40581428 - DOI: 10.1016/j.det.2025.03.004

Kim SH, Tsao H

Acral Melanoma: A Review of Its Pathogenesis, Progression, and Management.
Biomolecules. 2025;15(1):ePub - PMID: 39858514 - PMCID: PMC11763010 - DOI: 10.3390/biom15010120

Poudel K, Vithiananthan T, Kim JO, Tsao H

Recent progress in cancer vaccines and nanovaccines.
Biomaterials. 2024;314:122856 - PMID: 39366184 - DOI: 10.1016/j.biomaterials.2024.122856

Latoni DI, McDaniel DC, Tsao H, Tsao SS

Update on the Pathogenesis of Keloid Formation.
JID Innov. 2024;4(6):100299 - PMID: 39247523 - PMCID: PMC11378114 - DOI: 10.1016/j.xjidi.2024.100299

Everdell E, Borok J, Deutsch A, Ren Z, Cohen JV, Molina G, Vangala S, McDaniel D, Tsao H

ATLAS: A positive, high-yield review of patient symptoms most significantly associated with melanoma recurrence.
J Am Acad Dermatol. 2024;91(6):1118-1124 - PMID: 39197498 - DOI: 10.1016/j.jaad.2024.07.1516

Latoni DI, Semenov YR, Tsao H

Differential time series analysis shows deceleration in melanoma mortality prior to the widespread use of highly effective therapies.
J Am Acad Dermatol. 2024;91(5):872-879 - PMID: 39038555 - PMCID: PMC11653201 - DOI: 10.1016/j.jaad.2024.07.1457

Poudel K, Ji Z, Njauw CN, Rajadurai A, Bhayana B, Sullivan RJ, Kim JO, Tsao H

Fabrication and functional validation of a hybrid biomimetic nanovaccine (HBNV) against Kit K641E -mutant melanoma.
Bioact Mater. 2024;46:347-364 - PMID: 39834347 - PMCID: PMC11742834 - DOI: 10.1016/j.bioactmat.2024.12.023

Usoltsev D, Njauw CN, Ji Z, Kumar R, Sergushichev A, Zhang S, Shlyakhto E, Daly MJ, Artomov M, Tsao H

Analysis of Variants Induced by Combined Ex Vivo Irradiation and In Vivo Tumorigenesis Suggests a Role for the ZNF831 p.R1393Q Variant in Cutaneous Melanoma Development.
J Invest Dermatol. 2024;145(7):1728-1739.e7 - PMID: 39675662 - DOI: 10.1016/j.jid.2024.08.042

Gupta S, Shaughnessy M, Rashid S, Stagner AM, Fewkes J, Marghoob AA, Tsao H

Lentigo Maligna Part II: Management.
J Am Acad Dermatol. 2024;93(6):1399-1410 - PMID: 39447752 - DOI: 10.1016/j.jaad.2024.07.1534

Gupta S, Shaughnessy M, Rashid S, Stagner AM, Fewkes J, Marghoob AA, Tsao H

Lentigo Maligna Part I: Epidemiology, Risk Factors, and Diagnosis.
J Am Acad Dermatol. 2024;93(6):1383-1396 - PMID: 39442885 - DOI: 10.1016/j.jaad.2024.09.065

Everdell E, Ji Z, Njauw CN, Tsao H

Molecular Analysis of Murine KitK641E Melanoma Progression.
JID Innov. 2024;4(3):100266 - PMID: 38585193 - PMCID: PMC10995915 - DOI: 10.1016/j.xjidi.2024.100266

Latoni DI, Foreman RK, Lavigne K, Busam KJ, Tsao H

Multiple de novo spitzoid nevi arising within a specific red tattoo ink.
JAAD Case Rep. 2024;46:78-80 - PMID: 38577501 - PMCID: PMC10992272 - DOI: 10.1016/j.jdcr.2024.02.012

Funchain P, Ni Y, Heald B, Bungo B, Arbesman M, Behera TR, McCormick S, Song JM, Kennedy LB, Nielsen SM, Esplin ED, Nizialek E, Ko J, Diaz-Montero CM, Gastman B, Stratigos AJ, Artomov M, Tsao H, Arbesman J

Germline cancer susceptibility in individuals with melanoma.
J Am Acad Dermatol. 2024;91(2):265-272 - PMID: 38513832 - DOI: 10.1016/j.jaad.2023.11.070

Latoni DI, Geller AC, Semenov YR, Ji Z, Tsao H

Geotemporal Analysis of Melanoma Incidence and Mortality Identifies Distinct Clusters of Trends within the United States Between 2001 and 2019.
J Invest Dermatol. 2024;145(2):393-399.e1 - PMID: 38981567 - PMCID: PMC11704087 - DOI: 10.1016/j.jid.2024.05.032

Win TS, Tsao H

Keratinocytic skin cancers-Update on the molecular biology.
Cancer. 2023;129(6):836-844 - PMID: 36645692 - DOI: 10.1002/cncr.34635

Tsao H, Tang C, Trembath M, Jones P, Snelling PJ

Ultrasound-guided supraclavicular block versus Bier block for emergency reduction of upper limb injuries: a protocol for an open-label, non-inferiority, randomised controlled trial.
Trials. 2023;24(1):366 - PMID: 37254224 - PMCID: PMC10230709 - DOI: 10.1186/s13063-023-07403-z

Everdell E, Denize T, Tsao H

Acquired brachial cutaneous dyschromatosis.
JAAD Case Rep. 2023;37:110-113 - PMID: 37396486 - PMCID: PMC10314224 - DOI: 10.1016/j.jdcr.2023.05.007

Wan G, Leung BW, DeSimone MS, Nguyen N, Rajeh A, Collier MR, Rashdan H, Roster K, Zhou X, Moseley CB, Nirmal AJ, Pelletier RJ, Maliga Z, Marko-Varga G, Németh IB, Tsao H, Asgari MM, Gusev A, Stagner AM, Lian CG, Hurlbert MS, Liu F, Yu KH, Sorger PK, Semenov YR

Development and validation of time-to-event models to predict metastatic recurrence of localized cutaneous melanoma.
J Am Acad Dermatol. 2023;90(2):288-298 - PMID: 37797836 - PMCID: PMC10843255 - DOI: 10.1016/j.jaad.2023.08.105

Rashid S, Molotkov I, Klebanov N, Shaughnessy M, Daly MJ, Artomov M, Tsao H

Mendelian Randomization Analysis reveals Inverse Genetic Risks between Skin Cancers and Vitiligo.
JID Innov. 2023;3(6):100217 - PMID: 38034848 - PMCID: PMC10685305 - DOI: 10.1016/j.xjidi.2023.100217

Sanna A, Phung B, Mitra S, Lauss M, Choi J, Zhang T, Njauw CN, Cordero E, Harbst K, Rosengren F, Cabrita R, Johansson I, Isaksson K, Ingvar C, Carneiro A, Brown K, Tsao H, Andersson M, Pietras K, Jönsson G

DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype.
JCI Insight. 2022;7(19):ePub - PMID: 36040798 - PMCID: PMC9675437 - DOI: 10.1172/jci.insight.156577

Rashid S, Gupta S, McCormick SR, Tsao H

New Insights into Melanoma Tumor Syndromes.
JID Innov. 2022;2(6):100152 - PMID: 36387771 - PMCID: PMC9641259 - DOI: 10.1016/j.xjidi.2022.100152

Jobbagy S, Chaudet KM, Gayhart M, Klepeis VE, Boland G, Tsao H, Duncan LM

Resilience of melanoma diagnostics at a tertiary-care hospital during the SARS-CoV-2 pandemic.
JAAD Int. 2022;9:78-79 - PMID: 36061239 - PMCID: PMC9428333 - DOI: 10.1016/j.jdin.2022.08.012

Rashid S, Shaughnessy M, Tsao H

Melanoma classification and management in the era of molecular medicine.
Dermatol Clin. 2022;41(1):49-63 - PMID: 36410983 - DOI: 10.1016/j.det.2022.07.017

Kang Y, Ji Z, Li H, Tsao H

Divergent BRAF Inhibitor Resistance Mechanisms Revealed through Epigenetic Mapping.
J Invest Dermatol. 2022;143(5):842-853.e6 - PMID: 36529262 - DOI: 10.1016/j.jid.2022.03.039

Rashid S, Tsao H

Recognition, Staging, and Management of Melanoma.
Med Clin North Am. 2021;105(4):643-661 - PMID: 34059243 - DOI: 10.1016/j.mcna.2021.04.005

Rashid S, Tsao H

Effect of the COVID-19 Pandemic on Delayed Skin Cancer Services.
Dermatol Clin. 2021;39(4):627-637 - PMID: 34556252 - PMCID: PMC8162820 - DOI: 10.1016/j.det.2021.05.015

Guhan SM, Shaughnessy M, Rajadurai A, Taylor M, Kumar R, Ji Z, Rashid S, Flaherty K, Tsao H

The Molecular Context of Vulnerability for CDK9 Suppression in Triple Wild-Type Melanoma.
J Invest Dermatol. 2021;141(8):2018-2027.e4 - PMID: 33745909 - PMCID: PMC8316294 - DOI: 10.1016/j.jid.2020.12.035

Coroiu A, Moran C, Davine JA, Brophy K, Bergeron C, Tsao H, Körner A, Swetter SM, Geller AC

Patient-identified early clinical warning signs of nodular melanoma: a qualitative study.
BMC Cancer. 2021;21(1):371 - PMID: 33827477 - PMCID: PMC8028760 - DOI: 10.1186/s12885-021-08072-4

Atkins MB, Curiel-Lewandrowski C, Fisher DE, Swetter SM, Tsao H, Aguirre-Ghiso JA, Soengas MS, Weeraratna AT, Flaherty KT, Herlyn M, Sosman JA, Tawbi HA, Pavlick AC, Cassidy PB, Chandra S, Chapman PB, Daud A, Eroglu Z, Ferris LK, Fox BA, Gershenwald JE, Gibney GT, Grossman D, Hanks BA, Hanniford D, Hernando E, Jeter JM, Johnson DB, Khleif SN, Kirkwood JM, Leachman SA, Mays D, Nelson KC, Sondak VK, Sullivan RJ, Merlino G, Melanoma Research Foundation

The State of Melanoma: Emergent Challenges and Opportunities.
Clin Cancer Res. 2021;27(10):2678-2697 - PMID: 33414132 - PMCID: PMC8127340 - DOI: 10.1158/1078-0432.CCR-20-4092

Njauw CN, Ji Z, Pham DM, Simoneau A, Kumar R, Flaherty KT, Zou L, Tsao H

Oncogenic KIT Induces Replication Stress and Confers Cell Cycle Checkpoint Vulnerability in Melanoma.
J Invest Dermatol. 2021;142(5):1413-1424.e6 - PMID: 34687746 - DOI: 10.1016/j.jid.2021.07.188

Pham DDM, Guhan S, Tsao H

KIT and Melanoma: Biological Insights and Clinical Implications.
Yonsei Med J. 2020;61(7):562-571 - PMID: 32608199 - PMCID: PMC7329741 - DOI: 10.3349/ymj.2020.61.7.562

Nguyen ED, Xue YK, Danesh M, Ameri A, Weng CQ, Klebanov N, Foreman RK, Nazarian RM, Demehri S, Tsao H, Kroshinsky D

A Case of Nivolumab-Induced Cutaneous Toxicity with Multiple Morphologies.
Dermatopathology (Basel). 2020;6(4):255-259 - PMID: 32232031 - PMCID: PMC7098352 - DOI: 10.1159/000505353

Kang Y, Roh MR, Rajadurai S, Rajadurai A, Kumar R, Njauw CN, Zheng Z, Tsao H

Hypoxia and HIF-1α Regulate Collagen Production in Keloids.
J Invest Dermatol. 2020;140(11):2157-2165 - PMID: 32315657 - DOI: 10.1016/j.jid.2020.01.036

Ji Z, Njauw CN, Guhan S, Kumar R, Reddy B, Rajadurai A, Flaherty K, Tsao H

Loss of ACK1 Upregulates EGFR and Mediates Resistance to BRAF Inhibition.
J Invest Dermatol. 2020;141(5):1317-1324.e1 - PMID: 33159968 - DOI: 10.1016/j.jid.2020.06.041

Guhan S, Boland G, Tanabe K, Lin W, Reddy B, Hawryluk EB, Sober AJ, Tsao H

Surgical delay and mortality for primary cutaneous melanoma.
J Am Acad Dermatol. 2020;84(4):1089-1091 - PMID: 32711092 - PMCID: PMC7375294 - DOI: 10.1016/j.jaad.2020.07.078

Beaulieu D, Tsao H, Michaud DS, Okhovat JP, Halpern AC, Lundberg M, Geller AC

A geographically based cross-sectional analysis of SPOT me skin cancer screening data.
J Am Acad Dermatol. 2020;84(3):809-810.e3 - PMID: 32534079 - PMCID: PMC9469797 - DOI: 10.1016/j.jaad.2020.06.014

Klebanov N, Artomov M, Goggins WB, Daly E, Daly MJ, Tsao H

Burden of unique and low prevalence somatic mutations correlates with cancer survival.
Sci Rep. 2019;9(1):4848 - PMID: 30890735 - PMCID: PMC6425006 - DOI: 10.1038/s41598-019-41015-5

Zhang AJ, Rush PS, Tsao H, Duncan LM

BRCA1-associated protein (BAP1)-inactivated melanocytic tumors.
J Cutan Pathol. 2019;46(12):965-972 - PMID: 31233225 - DOI: 10.1111/cup.13530

Shaughnessy M, Njauw CN, Artomov M, Tsao H

Classifying Melanoma by TERT Promoter Mutational Status.
J Invest Dermatol. 2019;140(2):390-394.e1 - PMID: 31425705 - PMCID: PMC6983338 - DOI: 10.1016/j.jid.2019.06.149

Shaughnessy M, Lamuraglia G, Klebanov N, Ji Z, Rajadurai A, Kumar R, Flaherty K, Tsao H

Selective uveal melanoma inhibition with calcium channel blockade.
Int J Oncol. 2019;55(5):1090-1096 - PMID: 31545410 - PMCID: PMC6776194 - DOI: 10.3892/ijo.2019.4873

Phung B, Cieśla M, Sanna A, Guzzi N, Beneventi G, Cao Thi Ngoc P, Lauss M, Cabrita R, Cordero E, Bosch A, Rosengren F, Häkkinen J, Griewank K, Paschen A, Harbst K, Olsson H, Ingvar C, Carneiro A, Tsao H, Schadendorf D, Pietras K, Bellodi C, Jönsson G

The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma.
Cell Rep. 2019;27(12):3573-3586.e7 - PMID: 31216476 - DOI: 10.1016/j.celrep.2019.05.069

Mitchell G, Tsao H, Randell T, Marks J, Mackay P

Impact of electric scooters to a tertiary emergency department: 8-week review after implementation of a scooter share scheme.
Emerg Med Australas. 2019;31(6):930-934 - PMID: 31423709 - DOI: 10.1111/1742-6723.13356

Kumar R, Njauw CN, Reddy BY, Ji Z, Rajadurai A, Klebanov N, Tsao H

Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma.
Oncogene. 2019;38(18):3504-3520 - PMID: 30651601 - PMCID: PMC6756020 - DOI: 10.1038/s41388-018-0632-2

Klebanov N, Lin WM, Artomov M, Shaughnessy M, Njauw CN, Bloom R, Eterovic AK, Chen K, Kim TB, Tsao SS, Tsao H

Use of Targeted Next-Generation Sequencing to Identify Activating Hot Spot Mutations in Cherry Angiomas.
JAMA Dermatol. 2019;155(2):211-215 - PMID: 30601876 - PMCID: PMC6440195 - DOI: 10.1001/jamadermatol.2018.4231

Beaulieu D, Tsao H, Michaud DS, Okhovat JP, Halpern AC, Geller AC

Number needed to screen for presumptive screening diagnoses among first-time SPOTme screening participants (1992-2010).
J Am Acad Dermatol. 2019;82(1):233-234 - PMID: 31228527 - PMCID: PMC7985849 - DOI: 10.1016/j.jaad.2019.06.027

Artomov M, Joseph V, Tiao G, Thomas T, Schrader K, Klein RJ, Kiezun A, Gupta N, Margolin L, Stratigos AJ, Kim I, Shannon K, Ellisen LW, Haber D, Getz G, Tsao H, Lipkin SM, Altshuler D, Offit K, Daly MJ

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.
Eur J Hum Genet. 2019;27(5):824-828 - PMID: 30718883 - PMCID: PMC6461796 - DOI: 10.1038/s41431-019-0346-0

Ameri AH, Mooradian MJ, Emerick KS, Park JC, Wirth LJ, Asgari MM, Tsao H, Lawrence D, Sullivan RJ, Demehri S

Immunotherapeutic strategies for cutaneous squamous cell carcinoma prevention in xeroderma pigmentosum.
Br J Dermatol. 2019;181(5):1095-1097 - PMID: 31102460 - DOI: 10.1111/bjd.18144

Klebanov N, Reddy BY, Husain S, Silvers DN, Grossman ME, Tsao H

Cutaneous Presentation of Mesothelioma With a Sarcomatoid Transformation.
Am J Dermatopathol. 2018;40(5):378-382 - PMID: 29059099 - PMCID: PMC6426128 - DOI: 10.1097/DAD.0000000000001023

Roh MR, Kumar R, Rajadurai A, Njauw C, Ryoo UH, Chung KY, Tsao H

Beta-catenin causes fibrotic changes in the extracellular matrix via upregulation of collagen I transcription.
Br J Dermatol. 2017;177(1):312-315 - PMID: 27639179 - DOI: 10.1111/bjd.15079

Tsao H, Fukunaga-Kalabis M, Herlyn M

Recent Advances in Melanoma and Melanocyte Biology.
J Invest Dermatol. 2017;137(3):557-560 - PMID: 28089201 - DOI: 10.1016/j.jid.2016.11.004

Torres A, Tsao H

Commentary: American Academy of Dermatology free skin cancer screening: 30 years of value.
J Am Acad Dermatol. 2017;76(1):181-182 - PMID: 27986146 - DOI: 10.1016/j.jaad.2016.08.045

Roh MR, Park KH, Chung KY, Shin SJ, Rha SY, Tsao H

Telomerase reverse transcriptase (TERT) promoter mutations in Korean melanoma patients.
Am J Cancer Res. 2017;7(1):134-138 - PMID: 28123854 - PMCID: PMC5250687

Roh MR, Eliades P, Gupta S, Grant-Kels JM, Tsao H

Cutaneous melanoma in women.
Int J Womens Dermatol. 2017;3(1 Suppl):S11-S15 - PMID: 28492033 - PMCID: PMC5419022 - DOI: 10.1016/j.ijwd.2017.02.003

Reddy BY, Miller DM, Tsao H

Somatic driver mutations in melanoma.
Cancer. 2017;123(S11):2104-2117 - PMID: 28543693 - DOI: 10.1002/cncr.30593

Haugh AM, Njauw CN, Bubley JA, Verzì AE, Zhang B, Kudalkar E, VandenBoom T, Walton K, Swick BL, Kumar R, Rana HQ, Cochrane S, McCormick SR, Shea CR, Tsao H, Gerami P

Genotypic and Phenotypic Features of BAP1 Cancer Syndrome: A Report of 8 New Families and Review of Cases in the Literature.
JAMA Dermatol. 2017;153(10):999-1006 - PMID: 28793149 - PMCID: PMC5710339 - DOI: 10.1001/jamadermatol.2017.2330

Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP

Defining Clonal Color in Fluorescent Multi-Clonal Tracking.
Sci Rep. 2016;6:24303 - PMID: 27073117 - PMCID: PMC4829845 - DOI: 10.1038/srep24303

Wang H, Osseiran S, Igras V, Nichols AJ, Roider EM, Pruessner J, Tsao H, Fisher DE, Evans CL

In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin.
Sci Rep. 2016;6:37986 - PMID: 27892516 - PMCID: PMC5125099 - DOI: 10.1038/srep37986

Tsao H, Weinstock MA

Visual Inspection and the US Preventive Services Task Force Recommendation on Skin Cancer Screening.
JAMA. 2016;316(4):398-400 - PMID: 27458944 - DOI: 10.1001/jama.2016.9850

Soura E, Stratigos AJ, Tsao H

Reply to: "The absence of multiple atypical nevi in germline CDKN2A mutations".
J Am Acad Dermatol. 2016;75(4):e159 - PMID: 27646764 - DOI: 10.1016/j.jaad.2016.05.002

Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H

Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling.
J Am Acad Dermatol. 2016;74(3):411-20; quiz 421-2 - PMID: 26892651 - PMCID: PMC4761106 - DOI: 10.1016/j.jaad.2015.08.037

Roh MR, Gupta S, Park KH, Chung KY, Lauss M, Flaherty KT, Jönsson G, Rha SY, Tsao H

Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival.
J Invest Dermatol. 2016;136(5):1002-1011 - PMID: 26854490 - DOI: 10.1016/j.jid.2016.01.024

Ratushny V, Kraft S, Moschella SL, Duncan LM, Lawrence DP, Tsao H

A Symmetric Eczematous Eruption Harboring Thousands of Melanocytic Lesions.
JAMA Dermatol. 2016;152(9):1021-4 - PMID: 27192392 - DOI: 10.1001/jamadermatol.2016.1150

Eliades P, Tsao H

New Insights into the Molecular Distinction of Dysplastic Nevi and Common Melanocytic Nevi-Highlighting the Keratinocyte-Melanocyte Relationship.
J Invest Dermatol. 2016;136(10):1933-1935 - PMID: 27664709 - DOI: 10.1016/j.jid.2016.01.008

Eliades P, Miller DM, Miao B, Kumar R, Taylor M, Buch S, Srinivasa SP, Flaherty KT, Tsao H

A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors.
Cancer Biol Ther. 2016;17(7):778-84 - PMID: 26810603 - PMCID: PMC4970529 - DOI: 10.1080/15384047.2016.1139267
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