Tearney Lab

Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM

Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.
Nat Med. 2020;26(2):300 - PMID: 31996837 - PMCID: PMC7545464 - DOI: 10.1038/s41591-020-0773-z

Gerbaud E, Arabucki F, Nivet H, Barbey C, Cetran L, Chassaing S, Seguy B, Lesimple A, Cochet H, Montaudon M, Laurent F, Bar O, Tearney GJ, Coste P

OCT and CMR for the Diagnosis of Patients Presenting With MINOCA and Suspected Epicardial Causes.
JACC Cardiovasc Imaging. 2020;13(12):2619-2631 - PMID: 32828786 - DOI: 10.1016/j.jcmg.2020.05.045

Ennamorati M, Vasudevan C, Clerkin K, Halvorsen S, Verma S, Ibrahim S, Prosper S, Porter C, Yeliseyev V, Kim M, Gardecki J, Sassi S, Tearney G, Cherayil BJ, Bry L, Seed B, Jain N

Intestinal microbes influence development of thymic lymphocytes in early life.
Proc Natl Acad Sci U S A. 2020;117(5):2570-2578 - PMID: 31964813 - PMCID: PMC7007548 - DOI: 10.1073/pnas.1915047117

Struyvenberg MR, de Groof AJ, Fonollà R, van der Sommen F, de With PHN, Schoon EJ, Weusten BLAM, Leggett CL, Kahn A, Trindade AJ, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Vieth M, Pouw RE, Curvers WL, Bergman JJ

Prospective development and validation of a volumetric laser endomicroscopy computer algorithm for detection of Barrett's neoplasia.
Gastrointest Endosc. 2020;93(4):871-879 - PMID: 32735947 - DOI: 10.1016/j.gie.2020.07.052

Gerbaud E, Weisz G, Tanaka A, Luu R, Osman HASH, Baldwin G, Coste P, Cognet L, Waxman S, Zheng H, Moses JW, Mintz GS, Akasaka T, Maehara A, Tearney GJ

Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound.
Eur Heart J Cardiovasc Imaging. 2020;21(6):640-652 - PMID: 31326995 - PMCID: PMC7237959 - DOI: 10.1093/ehjci/jez185

Adewale AT, Falk Libby E, Fu L, Lenzie A, Boitet ER, Birket SE, Petty CF, Johns JD, Mazur M, Tearney GJ, Copeland D, Durham C, Rowe SM

Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport.
Am J Respir Cell Mol Biol. 2020;63(3):362-373 - PMID: 32374624 - PMCID: PMC7462336 - DOI: 10.1165/rcmb.2019-0287OC

Wartak A, Schenk MS, Bühler V, Kassumeh SA, Birngruber R, Tearney GJ

Micro-optical coherence tomography for high-resolution morphologic imaging of cellular and nerval corneal micro-structures.
Biomed Opt Express. 2020;11(10):5920-5933 - PMID: 33149996 - PMCID: PMC7587290 - DOI: 10.1364/BOE.402971

Leung HM, Wang ML, Osman H, Abouei E, MacAulay C, Follen M, Gardecki JA, Tearney GJ

Imaging intracellular motion with dynamic micro-optical coherence tomography.
Biomed Opt Express. 2020;11(5):2768-2778 - PMID: 32499959 - PMCID: PMC7249806 - DOI: 10.1364/BOE.390782

Desissaire S, Schwarzhans F, Salas M, Wartak A, Fischer G, Vass C, Pircher M, Hitzenberger CK

Analysis of longitudinal sections of retinal vessels using Doppler OCT.
Biomed Opt Express. 2020;11(4):1772-1789 - PMID: 32341847 - PMCID: PMC7173918 - DOI: 10.1364/BOE.385938

Struyvenberg MR, de Groof AJ, Kahn A, Weusten BLAM, Fleischer DE, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Trindade AJ, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Leggett CL, Bergman JJGHM, Curvers WL

Multicenter study on the diagnostic performance of multiframe volumetric laser endomicroscopy targets for Barrett's esophagus neoplasia with histopathology correlation.
Dis Esophagus. 2020;33(12):ePub - PMID: 32607539 - PMCID: PMC7720006 - DOI: 10.1093/dote/doaa062

Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM

Excess mucus viscosity and airway dehydration impact COPD airway clearance.
Eur Respir J. 2020;55(1):ePub - PMID: 31672759 - PMCID: PMC7336367 - DOI: 10.1183/13993003.00419-2019

Feldman MB, Dutko RA, Wood MA, Ward RA, Leung HM, Snow RF, De La Flor DJ, Yonker LM, Reedy JL, Tearney GJ, Mou H, Hurley BP, Vyas JM

Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils.
Infect Immun. 2020;88(2):ePub - PMID: 31767773 - PMCID: PMC6977131 - DOI: 10.1128/IAI.00813-19

Elhardt C, Wertheimer CM, Wartak A, Zhao J, Leung HM, Kassumeh SA, Yin B, Tearney GJ, Birngruber R

Stromal Nerve Imaging and Tracking Using Micro-Optical Coherence Tomography.
Transl Vis Sci Technol. 2020;9(5):6 - PMID: 32821478 - PMCID: PMC7401960 - DOI: 10.1167/tvst.9.5.6

Chowdhury MM, Singh K, Albaghdadi MS, Khraishah H, Mauskapf A, Kessinger CW, Osborn EA, Kellnberger S, Piao Z, Lino Cardenas CL, Grau MS, Jaff MR, Rosenfield K, Libby P, Edelman ER, Lindsay ME, Tearney GJ, Jaffer FA

Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits.
JACC Basic Transl Sci. 2020;5(7):685-695 - PMID: 32760856 - PMCID: PMC7393431 - DOI: 10.1016/j.jacbts.2020.04.007

Birket SE, Davis JM, Fernandez-Petty CM, Henderson AG, Oden AM, Tang L, Wen H, Hong J, Fu L, Chambers A, Fields A, Zhao G, Tearney GJ, Sorscher EJ, Rowe SM

Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR.
Am J Respir Crit Care Med. 2020;202(9):1271-1282 - PMID: 32584141 - PMCID: PMC7605185 - DOI: 10.1164/rccm.202002-0369OC

Struyvenberg M, Kahn A, Fleischer D, Swager AF, Bouma B, Ganguly EK, Konda V, Lightdale CJ, Pleskow D, Sethi A, Smith M, Trindade AJ, Wallace MB, Wang K, Wolfsen HC, Tearney GJ, Curvers WL, Leggett CL, Bergman JJ

Expert assessment on volumetric laser endomicroscopy full scans in Barrett's esophagus patients with or without high grade dysplasia or early cancer.
Endoscopy. 2020;53(3):218-225 - PMID: 32515006 - DOI: 10.1055/a-1194-0397

Levink IJM, Tearney GJ, Erler NS, Wolfsen HC, Siersema PD, Wallace MB

Barrett's Epithelial Thickness, Assessed by Volumetric Laser Endomicroscopy, Is Associated With Response to Radiofrequency Ablation.
Clin Gastroenterol Hepatol. 2020;19(6):1160-1169.e2 - PMID: 32434069 - DOI: 10.1016/j.cgh.2020.05.023

Freeman EE, Semeere A, Laker-Oketta M, Namaganda P, Osman H, Lukande R, McMahon D, Seth D, Oyesiku L, Tearney GJ, Gonzalez S, Rajadhyaksha M, Anderson RR, Martin J, Kang D

Feasibility and implementation of portable confocal microscopy for point-of-care diagnosis of cutaneous lesions in a low-resource setting.
J Am Acad Dermatol. 2020;84(2):499-502 - PMID: 32376425 - PMCID: PMC7606307 - DOI: 10.1016/j.jaad.2020.04.147

Bhagavatula SK, Li L, Tearney GJ

Characterization of interventional photoacoustic imaging (iPAI) capabilities in biological tissues.
Med Phys. 2020;48(2):770-780 - PMID: 33264419 - DOI: 10.1002/mp.14630
19