Tearney Lab

Jaffer FA, Dweck MR, Tearney GJ, Libby P, Tawakol A

Cellular and molecular imaging of coronary atherosclerosis: clinical applications.
Eur Heart J. 2025;:ePub - PMID: 41222955 - DOI: 10.1093/eurheartj/ehaf804

Otuya DO, Farrokhi H, Verma Y, Dong J, Choy P, Kumar A, Shore RE, Zemlok SK, Sevieri E, Schellenberg M, Spicer G, Lopez DR, Osman HA, Gardecki JA, Kyrollos Kelada AAF, Gao AH, Chung A, Grant CN, Bhat NGM, Rosenberg M, Jacobson BC, Nishioka NS, Colson Y, Tearney GJ

A thin cryobiopsy device compatible with transnasal endoscopy for the gastrointestinal tract.
Sci Transl Med. 2025;17(796):eado9609 - PMID: 40305575 - DOI: 10.1126/scitranslmed.ado9609

Batts S, Pham N, Tearney G, Stankovic KM

The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.
Adv Sci (Weinh). 2025;12(28):e00556 - PMID: 40470704 - PMCID: PMC12302556 - DOI: 10.1002/advs.202500556

Schulz-Hildebrandt H, Gardecki JA, Miller T, Avila-Wallace M, Villareyna-Lopez E, Tearney G

Phase-sensitive dynamic micro-optical coherence tomography for high-speed intracellular motion imaging.
Opt Lett. 2025;50(15):4734-4737 - PMID: 40751978 - DOI: 10.1364/OL.563024

Photiou C, Thrapp A, Tearney G, Pitris C

Deep learning for the detection of colon polyps with malignant potential: ex vivo classification using feature-enhanced optical coherence tomography (OCT) images.
Biomed Opt Express. 2025;16(6):2543-2554 - PMID: 40677387 - PMCID: PMC12265449 - DOI: 10.1364/BOE.555185

Photiou C, Thrapp AD, Tearney GJ, Pitris C

Classification of colon polyps with malignant potential using statistical analysis of features extracted from ex vivo optical coherence tomography images.
Biomed Eng Online. 2025;24(1):108 - PMID: 41013623 - PMCID: PMC12465873 - DOI: 10.1186/s12938-025-01443-z

MacRobbie M, Chen VZ, Paige C, Otuya D, Stankovic A, Tearney G

Evaluating the Suitability of Perfusion-Based PD Probes for Use in Altered Gravity Environments.
Biosensors (Basel). 2025;15(8):ePub - PMID: 40862939 - PMCID: PMC12384861 - DOI: 10.3390/bios15080478

Rauschendorfer P, Thrapp A, Srinivas A, Carleton R, Mauskapf A, Griffin KN, Ntziachristos V, Tearney GJ, Jaffer FA

High-Speed Intravascular Near-infrared Fluorescence-Ultrasound Imaging In Vivo.
IEEE Trans Biomed Eng. 2025;PP:ePub - PMID: 40742867 - DOI: 10.1109/TBME.2025.3594136

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Nat Rev Cardiol. 2024;21(5):348 - PMID: 38110566 - PMCID: PMC11987009 - DOI: 10.1038/s41569-023-00982-z

Tufaro V, Jaffer FA, Serruys PW, Onuma Y, van der Steen AFW, Stone GW, Muller JE, Marcu L, Van Soest G, Courtney BK, Tearney GJ, Bourantas CV

Emerging Hybrid Intracoronary Imaging Technologies and Their Applications in Clinical Practice and Research.
JACC Cardiovasc Interv. 2024;17(17):1963-1979 - PMID: 39260958 - PMCID: PMC11996234 - DOI: 10.1016/j.jcin.2024.07.007

Harris ES, McIntire HJ, Mazur M, Schulz-Hildebrandt H, Leung HM, Tearney GJ, Krick S, Rowe SM, Barnes JW

Reduced sialylation of airway mucin impairs mucus transport by altering the biophysical properties of mucin.
Sci Rep. 2024;14(1):16568 - PMID: 39019950 - PMCID: PMC11255327 - DOI: 10.1038/s41598-024-66510-2

Singh AP, Göb M, Ahrens M, Eixmann T, Schulte B, Schulz-Hildebrandt H, Hüttmann G, Ellrichmann M, Huber R, Rahlves M

Virtual Hall sensor triggered multi-MHz endoscopic OCT imaging for stable real-time visualization.
Opt Express. 2024;32(4):5809-5825 - PMID: 38439298 - DOI: 10.1364/OE.514636

Liu G, Ahn SW, Kang JW, Bhagavatula S, Matthew D, Martin S, Marlin C, So PTC, Tearney GJ, Jonas O

Two-site microendoscopic imaging probe for simultaneous three-dimensional imaging at two anatomic locations in tissues.
Opt Lett. 2024;49(12):3312-3315 - PMID: 38875608 - PMCID: PMC11298057 - DOI: 10.1364/OL.525945

Dolling M, Buhl L, Birngruber R, Hüttmann G, Schulz-Hildebrandt H

Algorithm and software for field distortion correction in a commercial SD-OCT for corneal curvature assessment.
Appl Opt. 2024;63(10):2694-2703 - PMID: 38568554 - DOI: 10.1364/AO.505107

Kelly P, VanBuskirk K, Coomes D, Mouksassi S, Smith G, Jamil Z, Hossain MS, Syed S, Marie C, Tarr PI, Sullivan PB, Petri WA, Denno DM, Ahmed T, Mahfuz M, Ali SA, Moore SR, Ndao IM, Tearney GJ, Ömer H Yilmaz , Raghavan SS, Moskaluk CA, Liu TC, EEDBI Consortium

Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared with United States children.
Am J Clin Nutr. 2024;120 Suppl 1:S15-S30 - PMID: 39300660 - DOI: 10.1016/j.ajcnut.2024.02.028

Ali ZA, Dager A, Zúñiga M, Fonseca J, Arana C, Chamié D, Hill JM, Madder RD, Muller JE, Simonton CA, Tearney GJ, Stone GW

First-in-Human Experience With a Novel Multimodality DeepOCT-NIRS Intracoronary Imaging System.
J Soc Cardiovasc Angiogr Interv. 2024;3(4):101344 - PMID: 39130176 - PMCID: PMC11308831 - DOI: 10.1016/j.jscai.2024.101344

Otuya DO, Liu Z, Joseph R, Hanafy MA, Vijaykumar K, Stanford D, Raju SV, Baker EH, Rowe SM, Tearney GJ, Solomon GM

Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe.
Am J Physiol Lung Cell Mol Physiol. 2024;328(2):L313-L320 - PMID: 39601216 - PMCID: PMC12633724 - DOI: 10.1152/ajplung.00137.2024

Nishimiya K, Sharma G, Singh K, Ahsen OO, Gardecki JA, Tearney GJ

Imaging human coronary cholesterol/urate crystals with cross-polarized micro-optical coherence tomography.
Front Cardiovasc Med. 2024;11:1433227 - PMID: 39529973 - PMCID: PMC11551715 - DOI: 10.3389/fcvm.2024.1433227

Schulz-Hildebrandt H, Spasic S, Hou F, Ting KC, Batts S, Tearney G, Stankovic KM

Dynamic micro-optical coherence tomography enables structural and metabolic imaging of the mammalian cochlea.
Front Mol Neurosci. 2024;17:1436837 - PMID: 39449964 - PMCID: PMC11499234 - DOI: 10.3389/fnmol.2024.1436837

Harris ES, McIntire HJ, Mazur M, Schulz-Hildebrandt H, Leung HM, Tearney GJ, Krick S, Rowe SM, Barnes JW

Reduced Sialylation of Airway Mucin Impairs Mucus Transport by Altering the Biophysical Properties of Mucin.
Res Sq. 2024;:ePub - PMID: 38853971 - PMCID: PMC11160914 - DOI: 10.21203/rs.3.rs-4421613/v1

Ikegami R, Piao Z, Iglesias JF, Pilgrim T, Ha K, McCarthy JR, Castellanos MI, Kassab MB, Albagdadi MS, Mauskapf A, Spicer G, Kandzari DE, Edelman ER, Libby P, Heg D, Joner M, Tearney GJ, Jaffer FA

Ultrathin-strut versus thin-strut stent healing and outcomes in preclinical and clinical subjects.
EuroIntervention. 2024;20(10):e669-e680 - PMID: 38776143 - PMCID: PMC11100507 - DOI: 10.4244/EIJ-D-23-00563

Vijaykumar K, Leung HM, Barrios A, Wade J, Hathorne HY, Nichols DP, Tearney GJ, Rowe SM, Solomon GM

Longitudinal improvements in clinical and functional outcomes following initiation of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis.
Heliyon. 2024;10(8):e29188 - PMID: 38681615 - PMCID: PMC11052906 - DOI: 10.1016/j.heliyon.2024.e29188

Lever JEP, Turner KB, Fernandez CM, Leung HM, Hussain SS, Shei RJ, Lin VY, Birket SE, Chu KK, Tearney GJ, Rowe SM, Solomon GM

Metachrony drives effective mucociliary transport via a calcium-dependent mechanism.
Am J Physiol Lung Cell Mol Physiol. 2024;327(3):L282-L292 - PMID: 38860289 - PMCID: PMC11444503 - DOI: 10.1152/ajplung.00392.2023

Vijaykumar K, Leung HM, Barrios A, Fernandez-Petty CM, Solomon GM, Hathorne HY, Wade JD, Monroe K, Slaten KB, Li Q, Leal SM, Moates DB, Pierce HM, Olson KR, Currier P, Foster S, Marsden D, Tearney GJ, Rowe SM

COVID-19 Causes Ciliary Dysfunction as Demonstrated by Human Intranasal Micro-Optical Coherence Tomography Imaging.
Am J Respir Cell Mol Biol. 2023;69(5):592-595 - PMID: 38195114 - PMCID: PMC10633845 - DOI: 10.1165/rcmb.2023-0177LE

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Nat Rev Cardiol. 2022;19(10):684-703 - PMID: 35449407 - PMCID: PMC9982688 - DOI: 10.1038/s41569-022-00687-9

Liu G, Kang JW, Bhagavatula S, Ahn SW, So PTC, Tearney GJ, Jonas O

Bendable long graded index lens microendoscopy.
Opt Express. 2022;30(20):36651-36664 - PMID: 36258589 - PMCID: PMC9662600 - DOI: 10.1364/OE.468827

Chowdhury MM, Piao Z, Albaghdadi MS, Coughlin PA, Rudd JHF, Tearney GJ, Jaffer FA

Intravascular Fluorescence Molecular Imaging of Atherosclerosis.
Methods Mol Biol. 2022;2419:853-872 - PMID: 35238006 - PMCID: PMC9052094 - DOI: 10.1007/978-1-0716-1924-7_52

Yao S, Campbell PT, Ugai T, Gierach G, Abubakar M, Adalsteinsson V, Almeida J, Brennan P, Chanock S, Golub T, Hanash S, Harris C, Hathaway CA, Kelsey K, Landi MT, Mahmood F, Newton C, Quackenbush J, Rodig S, Schultz N, Tearney G, Tworoger SS, Wang M, Zhang X, Garcia-Closas M, Rebbeck TR, Ambrosone CB, Ogino S

Proceedings of the fifth international Molecular Pathological Epidemiology (MPE) meeting.
Cancer Causes Control. 2022;33(8):1107-1120 - PMID: 35759080 - PMCID: PMC9244289 - DOI: 10.1007/s10552-022-01594-7

Vijaykumar K, Leung HM, Barrios A, Fernandez-Petty CM, Solomon GM, Hathorne HY, Wade JD, Monroe K, Slaten KB, Li Q, Leal SM, Moates DB, Pierce HM, Olson KR, Currier P, Foster S, Marsden D, Tearney GJ, Rowe SM

COVID-19 Causes Ciliary Dysfunction as Demonstrated by Human Intranasal Micro-Optical Coherence Tomography Imaging.
bioRxiv. 2022;:ePub - PMID: 35860227 - PMCID: PMC9298131 - DOI: 10.1101/2022.07.08.499336

Sheil CJ, Wartak A, Spicer GLC, Tearney GJ

Extended depth of focus by self-imaging wavefront division with the mirror tunnel.
J Opt Soc Am A Opt Image Sci Vis. 2022;39(4):711-725 - PMID: 35471398 - PMCID: PMC9232290 - DOI: 10.1364/JOSAA.448848

Otuya DO, Dechene NM, Poshtupaka D, Judson S, Carlson CJ, Zemlok SK, Sevieri E, Choy P, Shore RE, De León-Peralta E, Cirio AA, Rihm TW, Krall AA, Gavgiotaki E, Dong J, Silva SL, Baillargeon A, Baldwin G, Gao AH, Jansa Z, Barrios A, Ryan E, Bhat NGM, Balmasheva I, Chung A, Grant CN, Bablouzian AL, Beatty M, Ahsen OO, Zheng H, Tearney GJ

Passively scanned, single-fiber optical coherence tomography probes for gastrointestinal devices.
Lasers Surg Med. 2022;54(7):935-944 - PMID: 35708124 - PMCID: PMC9541095 - DOI: 10.1002/lsm.23576

Lopez DR, Sgroi D, Krishnamourthy S, Tearney G

Is Real-Time Microscopy on the Horizon? A Brief Review of the Potential Future Directions in Clinical Breast Tumor Microscopy Implementation.
Virchows Arch. 2022;480(1):211-227 - PMID: 35218378 - DOI: 10.1007/s00428-022-03300-z

Li Q, Vijaykumar K, Philips SE, Hussain SS, Huynh VN, Fernandez-Petty CM, Lever JEP, Foote JB, Ren J, Campos-Gómez J, Daya FA, Hubbs NW, Kim H, Onuoha E, Boitet ER, Fu L, Leung HM, Yu L, Detchemendy TW, Schaefers LT, Tipper JL, Edwards LJ, Leal SM, Harrod KS, Tearney GJ, Rowe SM

Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection.
bioRxiv. 2022;:ePub - PMID: 35075457 - PMCID: PMC8786228 - DOI: 10.1101/2022.01.16.476016

Kunio M, Gardecki JA, Watanabe K, Nishimiya K, Verma S, Jaffer FA, Tearney GJ

Histopathological correlation of near infrared autofluorescence in human cadaver coronary arteries.
Atherosclerosis. 2022;344:31-39 - PMID: 35134654 - PMCID: PMC9106423 - DOI: 10.1016/j.atherosclerosis.2022.01.012

Kaza N, Lin VY, Stanford D, Hussain SS, Falk Libby E, Kim H, Borgonovi M, Conrath K, Mutyam V, Byzek SA, Tang LP, Trombley JE, Rasmussen L, Schoeb T, Leung HM, Tearney GJ, Raju SV, Rowe SM

Evaluation of a novel CFTR potentiator in COPD ferrets with acquired CFTR dysfunction.
Eur Respir J. 2022;60(1):ePub - PMID: 34916262 - PMCID: PMC10079430 - DOI: 10.1183/13993003.01581-2021

Osborn EA, Ughi GJ, Verjans JW, Piao Z, Gerbaud E, Albaghdadi M, Khraishah H, Kassab MB, Takx RAP, Cui J, Mauskapf A, Shen C, Yeh RW, Klimas MT, Tawakol A, Tearney GJ, Jaffer FA

Intravascular Molecular-Structural Assessment of Arterial Inflammation in Preclinical Atherosclerosis Progression.
JACC Cardiovasc Imaging. 2021;14(11):2265-2267 - PMID: 34419392 - PMCID: PMC8571057 - DOI: 10.1016/j.jcmg.2021.06.017

Albaghdadi MS, Ikegami R, Kassab MB, Gardecki JA, Kunio M, Chowdhury MM, Khamis R, Libby P, Tearney GJ, Jaffer FA

Near-Infrared Autofluorescence in Atherosclerosis Associates With Ceroid and Is Generated by Oxidized Lipid-Induced Oxidative Stress.
Arterioscler Thromb Vasc Biol. 2021;41(7):e385-e398 - PMID: 34011166 - PMCID: PMC8222195 - DOI: 10.1161/ATVBAHA.120.315612

Iwata H, Osborn EA, Ughi GJ, Murakami K, Goettsch C, Hutcheson JD, Mauskapf A, Mattson PC, Libby P, Singh SA, Matamalas J, Aikawa E, Tearney GJ, Aikawa M, Jaffer FA

Highly Selective PPARα (Peroxisome Proliferator-Activated Receptor α) Agonist Pemafibrate Inhibits Stent Inflammation and Restenosis Assessed by Multimodality Molecular-Microstructural Imaging.
J Am Heart Assoc. 2021;10(20):e020834 - PMID: 34632804 - PMCID: PMC8751880 - DOI: 10.1161/JAHA.121.020834

Iyer JS, Yin B, Stankovic KM, Tearney GJ

Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter.
Sci Rep. 2021;11(1):17932 - PMID: 34504113 - PMCID: PMC8429662 - DOI: 10.1038/s41598-021-95991-8

Wartak A, Kelada AK, Leon Alarcon PA, Bablouzian AL, Ahsen OO, Gregg AL, Wei Y, Bollavaram K, Sheil CJ, Farewell E, VanTol S, Smith R, Grahmann P, Baillargeon AR, Gardecki JA, Tearney GJ

Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy.
Biomed Opt Express. 2021;12(7):4308-4323 - PMID: 34457416 - PMCID: PMC8367220 - DOI: 10.1364/BOE.422453

Ikuta M, Wu TY, Mach AT, Altshuler A, Yan X, Houskeeper JH, Yamamoto A, Tatsumi S, Iwata KI, Ryu J, Zeidan A, Tearney GJ, Takeuchi S

RGB-color forward-viewing spectrally encoded endoscope using three orders of diffraction.
Biomed Opt Express. 2021;12(2):1036-1049 - PMID: 33680558 - PMCID: PMC7901315 - DOI: 10.1364/BOE.415852

Kellnberger S, Wissmeyer G, Albaghdadi M, Piao Z, Li W, Mauskapf A, Rauschendorfer P, Tearney GJ, Ntziachristos V, Jaffer FA

Intravascular molecular-structural imaging with a miniaturized integrated near-infrared fluorescence and ultrasound catheter.
J Biophotonics. 2021;14(10):e202100048 - PMID: 34164943 - PMCID: PMC8492488 - DOI: 10.1002/jbio.202100048

Otuya DO, Verma Y, Luu R, Farrrokhi H, Tearney GJ

Improved sensitivity roll-off in dual reference, buffered spectral-domain optical coherence tomography.
J Biomed Opt. 2021;26(2):ePub - PMID: 33569937 - PMCID: PMC7874967 - DOI: 10.1117/1.JBO.26.2.025001

Yonker LM, Marand A, Muldur S, Hopke A, Leung HM, De La Flor D, Park G, Pinsky H, Guthrie LB, Tearney GJ, Irimia D, Hurley BP

Neutrophil dysfunction in cystic fibrosis.
J Cyst Fibros. 2021;20(6):1062-1071 - PMID: 33589340 - PMCID: PMC8568301 - DOI: 10.1016/j.jcf.2021.01.012

Usui E, Matsumura M, Mintz GS, Zhou Z, Hada M, Yamaguchi M, Hoshino M, Kanaji Y, Sugiyama T, Murai T, Lee T, Yonetsu T, Kakuta T, Kunio M, Tearney GJ, Maehara A

Clinical outcomes of low-intensity area without attenuation and cholesterol crystals in non-culprit lesions assessed by optical coherence tomography.
Atherosclerosis. 2021;332:41-47 - PMID: 34384955 - DOI: 10.1016/j.atherosclerosis.2021.08.003

Schenk MS, Wartak A, Buehler V, Zhao J, Tearney GJ, Birngruber R, Kassumeh S

Advances in Imaging of Subbasal Corneal Nerves With Micro-Optical Coherence Tomography.
Transl Vis Sci Technol. 2021;10(13):22 - PMID: 34779835 - PMCID: PMC8606792 - DOI: 10.1167/tvst.10.13.22

Okoro C, Cunningham CR, Baillargeon AR, Wartak A, Tearney GJ

Modeling, optimization, and validation of an extended-depth-of-field optical coherence tomography probe based on a mirror tunnel.
Appl Opt. 2021;60(8):2393-2399 - PMID: 33690340 - DOI: 10.1364/AO.420591

Nishimiya K, Tearney G

Micro Optical Coherence Tomography for Coronary Imaging.
Front Cardiovasc Med. 2021;8:613400 - PMID: 33842560 - PMCID: PMC8032864 - DOI: 10.3389/fcvm.2021.613400

Kang D, Ozcan A, Tearney GJ

Introduction to Special Biomedical Optical Imaging Issue.
Lasers Surg Med. 2021;53(6):747 - PMID: 34245596 - DOI: 10.1002/lsm.23413

Galdi F, Pedone C, McGee CA, George M, Rice AB, Hussain SS, Vijaykumar K, Boitet ER, Tearney GJ, McGrath JA, Brown AR, Rowe SM, Incalzi RA, Garantziotis S

Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study.
Respir Res. 2021;22(1):30 - PMID: 33517896 - PMCID: PMC7847749 - DOI: 10.1186/s12931-020-01610-x

Dong J, Grant C, Vuong B, Nishioka N, Gao AH, Beatty M, Baldwin G, Baillargeon A, Bablouzian A, Grahmann P, Bhat N, Ryan E, Barrios A, Giddings S, Ford T, Beaulieu-Ouellet E, Hosseiny SH, Lerman I, Trasischker W, Reddy R, Singh K, Gora M, Hyun D, Quénéhervé L, Wallace M, Wolfsen H, Sharma P, Wang KK, Leggett CL, Poneros J, Abrams JA, Lightdale C, Leeds S, Rosenberg M, Tearney GJ

Feasibility and Safety of Tethered Capsule Endomicroscopy in Patients With Barrett's Esophagus in a Multi-Center Study.
Clin Gastroenterol Hepatol. 2021;20(4):756-765.e3 - PMID: 33549871 - PMCID: PMC8715859 - DOI: 10.1016/j.cgh.2021.02.008

Cho DY, Zhang S, Skinner DF, Lim DJ, Banks C, Grayson JW, Tearney GJ, Rowe SM, Woodworth BA

Ivacaftor restores delayed mucociliary transport caused by Pseudomonas aeruginosa-induced acquired cystic fibrosis transmembrane conductance regulator dysfunction in rabbit nasal epithelia.
Int Forum Allergy Rhinol. 2021;12(5):690-698 - PMID: 34704673 - PMCID: PMC9038953 - DOI: 10.1002/alr.22907

Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM

Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.
Nat Med. 2020;26(2):300 - PMID: 31996837 - PMCID: PMC7545464 - DOI: 10.1038/s41591-020-0773-z

Gerbaud E, Arabucki F, Nivet H, Barbey C, Cetran L, Chassaing S, Seguy B, Lesimple A, Cochet H, Montaudon M, Laurent F, Bar O, Tearney GJ, Coste P

OCT and CMR for the Diagnosis of Patients Presenting With MINOCA and Suspected Epicardial Causes.
JACC Cardiovasc Imaging. 2020;13(12):2619-2631 - PMID: 32828786 - DOI: 10.1016/j.jcmg.2020.05.045

Ennamorati M, Vasudevan C, Clerkin K, Halvorsen S, Verma S, Ibrahim S, Prosper S, Porter C, Yeliseyev V, Kim M, Gardecki J, Sassi S, Tearney G, Cherayil BJ, Bry L, Seed B, Jain N

Intestinal microbes influence development of thymic lymphocytes in early life.
Proc Natl Acad Sci U S A. 2020;117(5):2570-2578 - PMID: 31964813 - PMCID: PMC7007548 - DOI: 10.1073/pnas.1915047117

Struyvenberg MR, de Groof AJ, Fonollà R, van der Sommen F, de With PHN, Schoon EJ, Weusten BLAM, Leggett CL, Kahn A, Trindade AJ, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Vieth M, Pouw RE, Curvers WL, Bergman JJ

Prospective development and validation of a volumetric laser endomicroscopy computer algorithm for detection of Barrett's neoplasia.
Gastrointest Endosc. 2020;93(4):871-879 - PMID: 32735947 - DOI: 10.1016/j.gie.2020.07.052

Gerbaud E, Weisz G, Tanaka A, Luu R, Osman HASH, Baldwin G, Coste P, Cognet L, Waxman S, Zheng H, Moses JW, Mintz GS, Akasaka T, Maehara A, Tearney GJ

Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound.
Eur Heart J Cardiovasc Imaging. 2020;21(6):640-652 - PMID: 31326995 - PMCID: PMC7237959 - DOI: 10.1093/ehjci/jez185

Adewale AT, Falk Libby E, Fu L, Lenzie A, Boitet ER, Birket SE, Petty CF, Johns JD, Mazur M, Tearney GJ, Copeland D, Durham C, Rowe SM

Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport.
Am J Respir Cell Mol Biol. 2020;63(3):362-373 - PMID: 32374624 - PMCID: PMC7462336 - DOI: 10.1165/rcmb.2019-0287OC

Wartak A, Schenk MS, Bühler V, Kassumeh SA, Birngruber R, Tearney GJ

Micro-optical coherence tomography for high-resolution morphologic imaging of cellular and nerval corneal micro-structures.
Biomed Opt Express. 2020;11(10):5920-5933 - PMID: 33149996 - PMCID: PMC7587290 - DOI: 10.1364/BOE.402971

Leung HM, Wang ML, Osman H, Abouei E, MacAulay C, Follen M, Gardecki JA, Tearney GJ

Imaging intracellular motion with dynamic micro-optical coherence tomography.
Biomed Opt Express. 2020;11(5):2768-2778 - PMID: 32499959 - PMCID: PMC7249806 - DOI: 10.1364/BOE.390782

Desissaire S, Schwarzhans F, Salas M, Wartak A, Fischer G, Vass C, Pircher M, Hitzenberger CK

Analysis of longitudinal sections of retinal vessels using Doppler OCT.
Biomed Opt Express. 2020;11(4):1772-1789 - PMID: 32341847 - PMCID: PMC7173918 - DOI: 10.1364/BOE.385938

Struyvenberg MR, de Groof AJ, Kahn A, Weusten BLAM, Fleischer DE, Ganguly EK, Konda VJA, Lightdale CJ, Pleskow DK, Sethi A, Smith MS, Trindade AJ, Wallace MB, Wolfsen HC, Tearney GJ, Meijer SL, Leggett CL, Bergman JJGHM, Curvers WL

Multicenter study on the diagnostic performance of multiframe volumetric laser endomicroscopy targets for Barrett's esophagus neoplasia with histopathology correlation.
Dis Esophagus. 2020;33(12):ePub - PMID: 32607539 - PMCID: PMC7720006 - DOI: 10.1093/dote/doaa062

Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM

Excess mucus viscosity and airway dehydration impact COPD airway clearance.
Eur Respir J. 2020;55(1):ePub - PMID: 31672759 - PMCID: PMC7336367 - DOI: 10.1183/13993003.00419-2019

Feldman MB, Dutko RA, Wood MA, Ward RA, Leung HM, Snow RF, De La Flor DJ, Yonker LM, Reedy JL, Tearney GJ, Mou H, Hurley BP, Vyas JM

Aspergillus fumigatus Cell Wall Promotes Apical Airway Epithelial Recruitment of Human Neutrophils.
Infect Immun. 2020;88(2):ePub - PMID: 31767773 - PMCID: PMC6977131 - DOI: 10.1128/IAI.00813-19

Elhardt C, Wertheimer CM, Wartak A, Zhao J, Leung HM, Kassumeh SA, Yin B, Tearney GJ, Birngruber R

Stromal Nerve Imaging and Tracking Using Micro-Optical Coherence Tomography.
Transl Vis Sci Technol. 2020;9(5):6 - PMID: 32821478 - PMCID: PMC7401960 - DOI: 10.1167/tvst.9.5.6

Chowdhury MM, Singh K, Albaghdadi MS, Khraishah H, Mauskapf A, Kessinger CW, Osborn EA, Kellnberger S, Piao Z, Lino Cardenas CL, Grau MS, Jaff MR, Rosenfield K, Libby P, Edelman ER, Lindsay ME, Tearney GJ, Jaffer FA

Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits.
JACC Basic Transl Sci. 2020;5(7):685-695 - PMID: 32760856 - PMCID: PMC7393431 - DOI: 10.1016/j.jacbts.2020.04.007

Birket SE, Davis JM, Fernandez-Petty CM, Henderson AG, Oden AM, Tang L, Wen H, Hong J, Fu L, Chambers A, Fields A, Zhao G, Tearney GJ, Sorscher EJ, Rowe SM

Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR.
Am J Respir Crit Care Med. 2020;202(9):1271-1282 - PMID: 32584141 - PMCID: PMC7605185 - DOI: 10.1164/rccm.202002-0369OC

Struyvenberg M, Kahn A, Fleischer D, Swager AF, Bouma B, Ganguly EK, Konda V, Lightdale CJ, Pleskow D, Sethi A, Smith M, Trindade AJ, Wallace MB, Wang K, Wolfsen HC, Tearney GJ, Curvers WL, Leggett CL, Bergman JJ

Expert assessment on volumetric laser endomicroscopy full scans in Barrett's esophagus patients with or without high grade dysplasia or early cancer.
Endoscopy. 2020;53(3):218-225 - PMID: 32515006 - DOI: 10.1055/a-1194-0397

Levink IJM, Tearney GJ, Erler NS, Wolfsen HC, Siersema PD, Wallace MB

Barrett's Epithelial Thickness, Assessed by Volumetric Laser Endomicroscopy, Is Associated With Response to Radiofrequency Ablation.
Clin Gastroenterol Hepatol. 2020;19(6):1160-1169.e2 - PMID: 32434069 - DOI: 10.1016/j.cgh.2020.05.023

Freeman EE, Semeere A, Laker-Oketta M, Namaganda P, Osman H, Lukande R, McMahon D, Seth D, Oyesiku L, Tearney GJ, Gonzalez S, Rajadhyaksha M, Anderson RR, Martin J, Kang D

Feasibility and implementation of portable confocal microscopy for point-of-care diagnosis of cutaneous lesions in a low-resource setting.
J Am Acad Dermatol. 2020;84(2):499-502 - PMID: 32376425 - PMCID: PMC7606307 - DOI: 10.1016/j.jaad.2020.04.147

Bhagavatula SK, Li L, Tearney GJ

Characterization of interventional photoacoustic imaging (iPAI) capabilities in biological tissues.
Med Phys. 2020;48(2):770-780 - PMID: 33264419 - DOI: 10.1002/mp.14630

Yin B, Piao Z, Nishimiya K, Hyun C, Gardecki JA, Mauskapf A, Jaffer FA, Tearney GJ

3D cellular-resolution imaging in arteries using few-mode interferometry.
Light Sci Appl. 2019;8:104 - PMID: 31798843 - PMCID: PMC6872567 - DOI: 10.1038/s41377-019-0211-5

Leung HM, Birket SE, Hyun C, Ford TN, Cui D, Solomon GM, Shei RJ, Adewale AT, Lenzie AR, Fernandez-Petty CM, Zheng H, Palermo JH, Cho DY, Woodworth BA, Yonker LM, Hurley BP, Rowe SM, Tearney GJ

Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies.
Sci Transl Med. 2019;11(504):ePub - PMID: 31391319 - PMCID: PMC6886258 - DOI: 10.1126/scitranslmed.aav3505

Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC

2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine.
Angew Chem Int Ed Engl. 2019;58(38):13405-13410 - PMID: 31365775 - DOI: 10.1002/anie.201908377

Nishimiya K, Yin B, Piao Z, Ryu J, Osman H, Leung HM, Sharma G, Liang CP, Gardecki JA, Zheng H, Shimokawa H, Tearney GJ

Micro-Optical Coherence Tomography for Endothelial Cell Visualization in the Coronary Arteries.
JACC Cardiovasc Imaging. 2019;12(9):1878-1880 - PMID: 30878431 - PMCID: PMC7685219 - DOI: 10.1016/j.jcmg.2019.01.021

Liu Z, Mackay S, Gordon DM, Anderson JD, Haithcock DW, Garson CJ, Tearney GJ, Solomon GM, Pant K, Prabhakarpandian B, Rowe SM, Guimbellot JS

Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging.
Biomed Opt Express. 2019;10(10):5414-5430 - PMID: 31646055 - PMCID: PMC6788592 - DOI: 10.1364/BOE.10.005414

Liang CP, Dong J, Ford T, Reddy R, Hosseiny H, Farrokhi H, Beatty M, Singh K, Osman H, Vuong B, Baldwin G, Grant C, Giddings S, Gora MJ, Rosenberg M, Nishioka N, Tearney G

Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients.
Biomed Opt Express. 2019;10(3):1207-1222 - PMID: 30891340 - PMCID: PMC6420285 - DOI: 10.1364/BOE.10.001207

Zeidan A, Do D, Kang D, Ikuta M, Ryu J, Tearney GJ

High-Resolution, Wide-Field, Forward-Viewing Spectrally Encoded Endoscope.
Lasers Surg Med. 2019;51(9):808-814 - PMID: 31129921 - DOI: 10.1002/lsm.23102

Tearney GJ, Wang TD, Kang D

Introduction to Biomedical Optical Imaging Issue.
Lasers Surg Med. 2019;51(5):389 - PMID: 31115922 - DOI: 10.1002/lsm.23100

Mathur SC, Fitzmaurice M, Reder NP, Krishnamurthy S, Kennedy M, Tearney GJ, Shevchuk-Chaban MM

Development of Functional Requirements for Ex Vivo Pathology Applications of In Vivo Microscopy Systems: A Proposal From the In Vivo Microscopy Committee of the College of American Pathologists.
Arch Pathol Lab Med. 2019;143(9):1052-1057 - PMID: 30763117 - DOI: 10.5858/arpa.2018-0482-OA

Levink IJM, Wolfsen HC, Siersema PD, Wallace MB, Tearney GJ

Measuring Barrett's Epithelial Thickness with Volumetric Laser Endomicroscopy as a Biomarker to Guide Treatment.
Dig Dis Sci. 2019;64(6):1579-1587 - PMID: 30632054 - PMCID: PMC6522645 - DOI: 10.1007/s10620-018-5453-1

Kang D, Do D, Ryu J, Grant CN, Giddings SL, Rosenberg M, Hesterberg PE, Yuan Q, Garber JJ, Katz AJ, Tearney GJ

A miniaturized, tethered, spectrally-encoded confocal endomicroscopy capsule.
Lasers Surg Med. 2019;51(5):452-458 - PMID: 30614021 - PMCID: PMC7685220 - DOI: 10.1002/lsm.23050

Ge X, Tang H, Wang X, Liu X, Chen S, Wang N, Ni G, Yu X, Chen S, Liang H, Bo E, Wang L, Braganza CS, Xu C, Rowe SM, Tearney GJ, Liu L

Geometry-Dependent Spectroscopic Contrast in Deep Tissues.
iScience. 2019;19:965-975 - PMID: 31522119 - PMCID: PMC6745491 - DOI: 10.1016/j.isci.2019.08.046

Fernandez-Petty CM, Hughes GW, Bowers HL, Watson JD, Rosen BH, Townsend SM, Santos C, Ridley CE, Chu KK, Birket SE, Li Y, Leung HM, Mazur M, Garcia BA, Evans TIA, Libby EF, Hathorne H, Hanes J, Tearney GJ, Clancy JP, Engelhardt JF, Swords WE, Thornton DJ, Wiesmann WP, Baker SM, Rowe SM

A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.
JCI Insight. 2019;4(8):ePub - PMID: 30996141 - PMCID: PMC6538343 - DOI: 10.1172/jci.insight.125954

Cho DY, Skinner D, Mackey C, Lampkin HB, Elder JB, Lim DJ, Zhang S, McCormick J, Tearney GJ, Rowe SM, Woodworth BA

Herbal dry extract BNO 1011 improves clinical and mucociliary parameters in a rabbit model of chronic rhinosinusitis.
Int Forum Allergy Rhinol. 2019;9(6):629-637 - PMID: 30657641 - PMCID: PMC6555666 - DOI: 10.1002/alr.22290

Cho DY, Skinner D, Zhang S, Lazrak A, Lim DJ, Weeks CG, Banks CG, Han CK, Kim SK, Tearney GJ, Matalon S, Rowe SM, Woodworth BA

Korean Red Ginseng aqueous extract improves markers of mucociliary clearance by stimulating chloride secretion.
J Ginseng Res. 2019;45(1):66-74 - PMID: 33437158 - PMCID: PMC7790903 - DOI: 10.1016/j.jgr.2019.09.001

Hancock LA, Hennessy CE, Solomon GM, Dobrinskikh E, Estrella A, Hara N, Hill DB, Kissner WJ, Markovetz MR, Grove Villalon DE, Voss ME, Tearney GJ, Carroll KS, Shi Y, Schwarz MI, Thelin WR, Rowe SM, Yang IV, Evans CM, Schwartz DA

Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.
Nat Commun. 2018;9(1):5363 - PMID: 30560893 - PMCID: PMC6299094 - DOI: 10.1038/s41467-018-07768-9

Wells WA, Thrall M, Sorokina A, Fine J, Krishnamurthy S, Haroon A, Rao B, Shevchuk MM, Wolfsen HC, Tearney GJ, Hariri LP

In Vivo and Ex Vivo Microscopy: Moving Toward the Integration of Optical Imaging Technologies Into Pathology Practice.
Arch Pathol Lab Med. 2018;143(3):288-298 - PMID: 30525931 - DOI: 10.5858/arpa.2018-0298-RA

Wells WA, Harhen MT, Thrall MJ, Shevchuk MM, Tearney GJ, Hariri LP

In Vivo and Ex Vivo Microscopy: A Business Plan to Justify the Introduction of Similar Emerging Technologies Into Pathology Practice.
Arch Pathol Lab Med. 2018;143(3):299-304 - PMID: 30525933 - DOI: 10.5858/arpa.2018-0375-RA

Gardecki JA, Singh K, Wu CL, Tearney GJ

Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography.
Arch Pathol Lab Med. 2018;143(3):314-318 - PMID: 30550349 - DOI: 10.5858/arpa.2018-0135-OA

Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA

Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494

Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA

Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017
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