Anand S, Chan TA, Hasan T, Maytin EV. Current Prospects for Treatment of Solid Tumors via Photodynamic, Photothermal, or Ionizing Radiation Therapies Combined with Immune Checkpoint Inhibition (Review). Pharmaceuticals. 2021; 14 (5), 447.

Ashraf S, Agyapong J, Rohrbach P, Hasan T. OPD (Online Plasmodium Diagnosis): An ALA-PpIX based functional assay to predict active malaria. Photodiagnosis Photodyn Ther. 2021 Aug 30; 36:102510. doi: 10.1016/j.pdpdt.2021.102510. Epub ahead of print. PMID: 34474169.

Ashraf S, Khalid A, Kuriakose J, Palanisami A, Feng Y, Hasan T. REAP (Rapid Elimination of Active Plasmodium): A photodynamic strategy exploiting intrinsic kinetics of the parasite to combat severe malaria. J Photochem Photobiol B. 2021 Aug 13; 223:112286. doi: 10.1016/j.jphotobiol.2021.112286. Epub ahead of print. PMID: 34416476.

Bhandari C, Guirguis M, Savan NA, Shrivastava N, Oliveira S, Hasan T, Obaid G. What NIR photodynamic activation offers molecular targeted nanomedicines: Perspectives into the conundrum of tumor specificity and selectivity. Nano Today. 2021 Feb; 36:101052. doi: 10.1016/j.nantod.2020.101052. Epub 2020 Dec 16. PMID: 33552231; PMCID: PMC7864390.

De Silva P, Bano S, Pogue BW, Wang KK, Maytin EV, Hasan H. Photodynamic priming with triple-receptor targeted nanoconjugates that trigger T cell-mediated immune responses in a 3D in vitro heterocellular model of pancreatic cancer. J. Nanophotonics. (on-line)

Feng Y, Coradi Tonon C, Ashraf S, Hasan T. Photodynamic and antibiotic therapy in combination against bacterial infections: efficacy, determinants, mechanisms, and future perspectives. Adv Drug Deliv Rev. 2021 Aug 19; 177:113941. doi: 10.1016/j.addr.2021.113941. Epub ahead of print. PMID: 34419503.

Feng Y, Swain JWR, Palanisami A, Ashr.af S, Hasan T. One-Step Detection and Classification of Bacterial Carbapenemases in 10 Minutes Using Fluorescence Identification of β-Lactamase Activity. J Clin Microbiol. 2021 Aug 18; 59(9):e0251720. doi: 10.1128/JCM.02517-20. Epub 2021 Aug 18. PMID: 34133891; PMCID: PMC8373032.

Guirguis M, Bhandari C, Li J, Eroy M, Prajapati S, Margolis R, Shrivastava N, Hoyt K, Hasan T, Obaid G. Membrane composition is a functional determinant of NIR-activable liposomes in orthotopic head and neck cancer. Nanophotonics. vol. 10, no. 12, 2021, pp. 3169-3185.

Hanada Y, Pereira SP, Pogue B, Maytin EV, Hasan T, Linn B, Mangels-Dick T, Wang KK. EUS-guided verteporfin photodynamic therapy for pancreatic cancer. Gastrointest Endosc. 2021 Feb 26:S0016-5107(21)00177-2. doi: 10.1016/j.gie.2021.02.027. Epub ahead of print. PMID: 33647286.

Kessel DH, Arany P, Hasan T, Carroll JD, Liebert A. Mechanisms and Techniques in Photodynamic Therapy and Photobiomodulation. (Proceeding of SPIE) 2021; vol. 11628: 1162801-1.

Mallidi S, Xavierselvan M, Mai Z, Hasan T. Can photoacoustic imaging to predict cellular photodynamic therapy efficacy? Photons Plus Ultrasound: Imaging and Sensing. 2021; 11642: 116424F.

Obaid G, Samkoe K, Tichauer K, Bano S, Park Y, Silber Z, Hodge S, Callaghan S, Guirguis M, Mallidi S, Pogue B, Hasan T. Is Tumor Cell Specificity Distinct from Tumor Selectivity In Vivo?: A Quantitative NIR Molecular Imaging Analysis of Nanoliposome Targeting. Nano Res. 2021 May; 14(5):1344-1354. doi: 10.1007/s12274-020-3178-x. Epub 2020 Nov 27. PMID: 33717420; PMCID: PMC7951968.

Saad MA, Xavierselvan M, Sharif HA, Selfridge S, Pawle R, Varvares M, Mallidi S, Hasan T. Dual Function Antibody Conjugates for Multimodal Imaging and Photoimmunotherapy of Cancer Cells. Photochem Photobiol. 2021 Aug 11. doi: 10.1111/php.13501. Epub ahead of print. PMID: 34379796.

Tonon CC, Ashraf S, Alburquerque JQ, de Souza Rastelli AN, Hasan T, Lyons AM, Greer A. Antimicrobial Photodynamic Inactivation Using Topical and Superhydrophobic Sensitizer Techniques: A Perspective from Diffusion in Biofilms†. Photochem Photobiol. 2021 Jun 7. doi: 10.1111/php.13461. Epub ahead of print. PMID: 34097752.

Vincent P, Bruza P, Palisoul SM, Gunn JR, Samkoe KS, Hoopes PJ, Hasan T, Pogue BW. Visualization and quantification of pancreatic tumor stroma in fresh tissue via ultraviolet surface excitation. J Biomed Opt. 2021 Jan; 26(1):016002. doi: 10.1117/1.JBO.26.1.016002. PMID: 33423407; PMCID: PMC7850982.

Vincent P, Maeder ME, Hunt B, Linn B, Mangels-Dick T, Hasan T, Wang KK, Pogue BW. CT radiomic features of photodynamic priming in clinical pancreatic adenocarcinoma treatment. Phys Med Biol. 2021 Aug 23; 66(17). doi: 10.1088/1361-6560/ac1458. PMID: 34261044.


Anbil S, Pigula M, Huang HC, Mallidi S, Broekgaarden M, Baglo Y, De Silva P, Simeone DM, Mino-Kenudson M, Maytin EV, Rizvi I, Hasan T. Vitamin D receptor activation and photodynamic priming enable durable low-dose chemotherapy. Mol Cancer Ther. 2020 Mar 27. pii: molcanther.0791.2019. doi: 10.1158/1535-7163.MCT-19-0791. [Epub ahead of print] PubMed PMID: 32220968.

Bano S, Obaid G, Swain JWR, Yamada M, Pogue BW, Wang K, Hasan T. NIR Photodynamic Destruction of PDAC and HNSCC Nodules Using Triple-Receptor-Targeted Photoimmuno-Nanoconjugates: Targeting Heterogeneity in Cancer. J Clin Med. 2020 Jul 27; 9(8):2390. doi: 10.3390/jcm9082390. PMID: 32726945; PMCID: PMC7464411.

Broekgaarden M, Alkhateeb A, Bano S, Bulin L, Obaid G, Rizi I, Hasan T. Cabozantinib Inhibits Photodynamic Therapy-Induced Auto- and Paracrine MET Signaling in Heterotypic Pancreatic Microtumors. Cancers (Basel). 2020 Jun; 12(6): 1401. Published online 2020 May 29. doi: 10.3390/cancers12061401. PMCID: PMC7352584.

De Silva P, Saad MA, Thomsen HC, Bano S, Ashraf S, Hasan T. Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization - a Thomas Dougherty Award for Excellence in PDT paper. J. Porphyrins Phthalocyanines. 2020; 24: 1320–1360.

Feng Y, Palanisami A, Kuriakose J, Pigula M, Ashraf S, Hasan T. Novel Rapid Test for Detecting Carbapenemase. Emerg Infect Dis. 2020 Apr; 26(4):793-795. doi: 10.3201/eid2604.181655. PubMed PMID: 32186503; PubMed Central PMCID: PMC7101118.

Feng Y, Palanisami A, Ashraf S, Bhayana B, Hasan T. Photodynamic inactivation of bacterial carbapenemases restores bacterial carbapenem susceptibility and enhances carbapenem antibiotic effectiveness. Photodiagnosis Photodyn Ther. 2020 Jun; 30:101693. doi: 10.1016/j.pdpdt.2020.101693. Epub 2020 Mar 12. PMID: 32173586.

Fisher C, Obaid G, Niu C, Foltz W, Goldstein A, Hasan T, Lilge L. Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma. J Clin Med. 2019 Dec 14; 8(12). pii: E2214. doi: 10.3390/jcm8122214. PMID: 31847378 DOI: 10.3390/jcm8122214.

Hasan T, Kessel D, Greer A. Preface: Memorial Issue Dedicated to Thomas J. Dougherty. Photochem Photobiol. 2020 May; 96(3):453. doi: 10.1111/php.13266. PMID: 32531143.

Khan S, Hussain MAB, Khan AP, Liu H, Siddiqui S, Mallidi S, Leon P, Daly L, Rudd G, Cuckov F, Hopper C, Bown SG, Akhtar K, Hasan SA, Siddiqui SA, Hasan T, Celli JP. Clinical evaluation of smartphone-based fluorescence imaging for guidance and monitoring of ALA-PDT treatment of early oral cancer. J Biomed Opt. 2020 Jun; 25(6): 063813. Published online 2020 Apr 11. doi: 10.1117/1.JBO.25.6.063813. PMCID: PMC7148420.

LaRochelle EPM, Chapman MS, Maytin EV, Hasan T, Pogue BW. Weather-informed Light-tissue Model-Based Dose Planning for Indoor Daylight Photodynamic Therapy. Photochem Photobiol. 2020 Mar; 96(2):320-326. doi: 10.1111/php.13170. Epub 2019 Oct 21. PMID: 31581341; PMCID: PMC7117968.

Maytin EV, Hasan T. Vitamin D and other differentiation-promoting agents as neoadjuvants for photodynamic therapy of cancer. Photochem Photobiol. 2020 Feb 19. doi: 10.1111/php.13230. [Epub ahead of print] Review. PubMed PMID: 32077114.

Nath S, Pigula M, Khan AP, Hanna W, Ruhi MK, Dehkordy FM, Pushpavanam K, Rege K, Moore K, Tsujita Y, Conrad C, Inci F, Carmen MGD, Franco W, Celli JP, Demirci U, Hasan T, Huang HC, Rizvi I. Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress. J Clin Med. 2020 Mar 28; 9(4). pii: E924. doi: 10.3390/jcm9040924. PubMed PMID: 32231055.

Ruiz AJ, LaRochelle EPM, Gunn JR, Hull SM, Hasan T, Chapman MS, Pogue BW. Smartphone fluorescence imager for quantitative dosimetry of protoporphyrin-IX-based photodynamic therapy in skin. J Biomed Opt. Dec; 25(6):1-13. doi: 10.1117/1.JBO.25.6.063802. PMID: 31820594 PMCID: PMC6901011 [Available on 2020-12-09] DOI: 10.1117/1.JBO.25.6.063802.

Liang BJ, Pigula M, Baglo Y, Najafali D, Hasan T, Huang HC. Breaking the selectivity-uptake trade-off of photoimmunoconjugates with nanoliposomal irinotecan for synergistic multi-tier cancer targeting. J Nanobiotechnology. 2020 Jan 2;18(1):1. PMCID: PMC6939330

Vincent P, Pogue B, Wang H, Nieskoski M, Gunn JR, Marra K, Hoopes J, Samkoe KS, Doyley M, Hasan T. High-resolution ex vivo elastography to characterize tumor stromal heterogeneity in situ in pancreatic adenocarcinoma. IEEE Trans Biomed Eng. 2020 Jan 1. [Epub ahead of print]


Broekgaarden M, Anbil S, Bulin AL, Obaid G, Mai Z, Baglo Y, Rizvi I, Hasan T. Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer. Biomaterials. 2019 Nov;222:119421. PMCID: PMC6934357 [Available on 2020-11-01]

Broekgaarden M, Bulin AL, Frederick J, Mai Z, Hasan T. Tracking Photodynamic- and Chemotherapy-Induced Redox-State Perturbations in 3D Culture Models of Pancreatic Cancer: A Tool for Identifying Therapy-Induced Metabolic Changes. J Clin Med. 2019 Sep 6;8(9). PMCID: PMC6788194

Bulin AL, Broekgaarden M, Simeone D, Hasan T. Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids. Oncotarget. 2019 Apr 5;10(27):2625-2643. PMCID: PMC6499000

Fisher C, Obaid G, Niu C, Foltz W, Goldstein A, Hasan T, Lilge L. Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma. J Clin Med. 2019 Dec 14;8(12). PMCID: PMC6947404

LaRochelle EPM, Chapman MS, Maytin EV, Hasan T, Pogue BW. Weather-informed Light-tissue Model-Based Dose Planning for Indoor Daylight Photodynamic Therapy. Photochem Photobiol. 2019 Oct 3. [Epub ahead of print]

Liu H, Daly L, Rudd G, Khan AP, Mallidi S, Liu Y, Cuckov F, Hasan T, Celli JP. Development and evaluation of a low-cost, portable, LED-based device for PDT treatment of early-stage oral cancer in resource-limited settings. Lasers Surg Med. 2019 Apr;51(4):345-351. PMCID: PMC6934354 [Available on 2020-04-01]

Lu J, Roy B, Anderson M, Leggett CL, Levy MJ, Pogue B, Hasan T, Wang KK. Verteporfin- and sodium porfimer-mediated photodynamic therapy enhances pancreatic cancer cell death without activating stromal cells in the microenvironment. J Biomed Opt. 2019 Nov;24(11):1-11.

Mallidi S, Khan AP, Liu H, Daly L, Rudd G, Leon P, Khan S, Hussain BMA, Hasan SA, Siddique SA, Akhtar K, August M, Troulis M, Cuckov F, Celli JP, Hasan T. Platform for ergonomic intraoral photodynamic therapy using low-cost, modular 3D-printed components: Design, comfort and clinical evaluation. Sci Rep. 2019 Nov 1;9(1):15830. PMCID: PMC6825190

Nath S, Obaid G, Hasan T. The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire. Photochem Photobiol. 2019 Nov;95(6):1288-1305. PMCID: PMC6878142 [Available on 2020-11-10]

Nath S, Saad MA, Pigula M, Swain JWR, Hasan T. Photoimmunotherapy of Ovarian Cancer: A Unique Niche in the Management of Advanced Disease. Cancers (Basel). 2019 Nov 27;11(12. PMCID: PMC6966499

Obaid G, Bano S, Mallidi S, Broekgaarden M, Kuriakose J, Silber Z, Bulin AL, Wang Y, Mai Z, Jin W, Simeone D, Hasan T. Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates: Towards Conquering Desmoplasia? Nano Lett. 2019 Nov 13;19(11):7573-7587. PMCID: PMC6934365 [Available on 2020-11-13]

Obaid G, Jin W, Bano S, Kessel D, Hasan T. Nanolipid Formulations of Benzoporphyrin Derivative: Exploring the Dependence of Nanoconstruct Photophysics and Photochemistry on Their Therapeutic Index in Ovarian Cancer Cells. Photochem Photobiol. 2019 Jan;95(1):364-377. PMCID: PMC6347486

Pigula M, Huang HC, Mallidi S, Anbil S, Liu J, Mai Z, Hasan T. Size-dependent Tumor Response to Photodynamic Therapy and Irinotecan Monotherapies Revealed by Longitudinal Ultrasound Monitoring in an Orthotopic Pancreatic Cancer Model. Photochem Photobiol. 2019 Jan;95(1):378-386. PMCID: PMC6905616

Rizvi I, Nath S, Obaid G, Ruhi MK, Moore K, Bano S, Kessel D, Hasan T. A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer. Photochem Photobiol. 2019 Jan;95(1):419-429.

Ruiz AJ, LaRochelle EPM, Gunn JR, Hull SM, Hasan T, Chapman MS, Pogue BW. Smartphone fluorescence imager for quantitative dosimetry of protoporphyrin-IX-based photodynamic therapy in skin. J Biomed Opt. 2019 Dec;25(6):1-13. PMCID: PMC6901011 [Available on 2020-12-09]

Spring BQ, Lang RT, Kercher EM, Rizvi I, Wenham RM, Conejo-Garcia JR, Hasan T, Gatenby RA, Enderling H. Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies. Front Phys. 2019 Apr;7. pii: 46. PMCID: PMC6529192


Broekgaarden M, Rizvi I, Bulin AL, Petrovic L, Goldschmidt R, Massodi I, Celli JP, Hasan T. Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids. Oncotarget. 2018 Feb 6;9(16):13009-13022. PMCID: PMC5849191

Bulin AL, Broekgaarden M, Hasan T. Comprehensive high-throughput image analysis for therapeutic efficacy of architecturally complex heterotypic organoids. Sci Rep. 2017 Nov 30;7(1):16645. PMCID: PMC5709388

Huang HC, Liu J, Baglo Y, Rizvi I, Anbil S, Pigula M, Hasan T. Mechanism-informed Repurposing of Minocycline Overcomes Resistance to Topoisomerase Inhibition for Peritoneal Carcinomatosis. Mol Cancer Ther. 2018 Feb;17(2):508-520. PMCID: PMC5805648

Huang HC, Pigula M, Fang Y, Hasan T. Immobilization of Photo-Immunoconjugates on Nanoparticles Leads to Enhanced Light-Activated Biological Effects. Small. 2018 Jul 1:e1800236. PMCID: PMC6312758

Huang HC, Rizvi I, Liu J, Anbil S, Kalra A, Lee H, Baglo Y, Paz N, Hayden D, Pereira S, Pogue BW, Fitzgerald J, Hasan T. Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery. Cancer Res. 2018 Jan 15;78(2):558-571. PMCID: PMC5771811

Marra K, LaRochelle EP, Chapman MS, Hoopes PJ, Lukovits K, Maytin EV, Hasan T, Pogue BW. Comparison of Blue and White Lamp Light with Sunlight for Daylight-Mediated, 5-ALA Photodynamic Therapy, in vivo. Photochem Photobiol. 2018 Sep;94(5):1049-1057. PMCID: PMC6135665 [Available on 2019-09-01]

Rizvi I, Obaid G, Bano S, Hasan T, Kessel D. Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent. Lasers Surg Med. 2018 Jul;50(5):499-505.


Anand S, Rollakanti KR, Brankov N, Brash DE, Hasan T, Maytin EV. Fluorouracil enhances photodynamic therapy of squamous cell carcinoma via a p53 -independent mechanism that increases protoporphyrin IX levels and tumor cell death. Mol Cancer Ther. 2017 Jun;16(6):1092-1101. PMCID: PMC5497500

Bulin AL, Broekgaarden M, Hasan T. Comprehensive high-throughput image analysis for therapeutic efficacy of architecturally complex heterotypic organoids. Sci Rep. 2017 Nov 30;7(1):16645. PMCID: PMC5709388

de Souza ALR, LaRochelle E, Marra K, Gunn J, Davis SC, Samkoe KS, Chapman MS, Maytin EV, Hasan T, Pogue BW. Assessing daylight & low-light photodynamic therapy efficacy, using biomarkers of photophysical, biochemical and biological damage metrics in situ. Photodiagnosis Photodyn Ther. 2017 Dec;20:227-233. PMCID: PMC5718943

Lee HH, Choi MG, Hasan T. Application of photodynamic therapy in gastrointestinal disorders: an outdated or re-emerging technique? Korean J Intern Med. 2017 Jan;32(1):1-10. PMCID: PMC5214731

Nieskoski MD, Marra K, Gunn JR, Kanick SC, Doyley MM, Hasan T, Pereira SP, Stuart Trembly B, Pogue BW. Separation of Solid Stress From Interstitial Fluid Pressure in Pancreas Cancer Correlates With Collagen Area Fraction. J Biomech Eng. 2017 Jun 1;139(6).

Nieskoski MD, Marra K, Gunn JR, Hoopes PJ, Doyley MM, Hasan T, Trembly BS, Pogue BW. Collagen Complexity Spatially Defines Microregions of Total Tissue Pressure in Pancreatic Cancer. Sci Rep. 2017 Aug 30;7(1):10093. PMCID: PMC5577321

Obaid G, Spring BQ, Bano S, Hasan T. Activatable clinical fluorophore-quencher antibody pairs as dual molecular probes for the enhanced specificity of image-guided surgery. J Biomed Opt. 2017 Aug;22(12):1-6. PMCID: PMC5574035


de Souza AL, Marra K, Gunn J, Samkoe KS, Kanick SC, Davis SC, Chapman MS, Maytin EV, Hasan T, Pogue BW. Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer. Br J Cancer. 2016 Sep 27;115(7):805-13. PMCID: PMC5046214

Huang HC, Mallidi S, Liu J, Chiang CT, Mai Z, Goldschmidt R, Ebrahim-Zadeh N, Rizvi I, Hasan T. Photodynamic therapy synergizes with irinotecan to overcome compensatory mechanisms and improve treatment outcomes in pancreatic cancer. Cancer Res. 2016 Mar 1;76(5):1066-77. PMCID: PMC4775276

Kim IW, Park JM, Roh YJ, Kim JH, Choi MG, Hasan T. Direct measurement of singlet oxygen by using a photomultiplier tube-based detection system. J Photochem Photobiol B. 2016 Mar 12;159:14-23.

Mallidi S, Anbil S, Bulin AL, Obaid G, Ichikawa M, Hasan T. Beyond the Barriers of Light Penetration: Strategies, Perspectives and Possibilities for Photodynamic Therapy. Theranostics. 2016 Oct 23;6(13):2458-2487. Review. PMCID: PMC5118607

Obaid G, Broekgaarden M, Bulin AL, Huang HC, Kuriakose J, Liu J, Hasan T. Photonanomedicine: a convergence of photodynamic therapy and nanotechnology. Nanoscale. 2016 Jul 7;8(25):12471-503. PMCID: PMC4956486

Palanisami A, Khan S, Erdem SS, Hasan T. Guiding Empiric Treatment for Serious Bacterial Infections via Point of Care [Formula: see text]-Lactamase Characterization. IEEE J Transl Eng Health Med. 2016 Jun 29;4:2800410. PMCID: PMC5003167

Pogue BW, Elliott JT, Kanick SC, Davis SC, Samkoe KS, Maytin EV, Pereira SP, Hasan T. Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success. Phys Med Biol. 2016 Apr 7;61(7):R57-89.

Pogue BW, Paulsen KD, Samkoe KS, Elliott JT, Hasan T, Strong TV, Draney DR, Feldwisch J. Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention. Med Phys. 2016 Jun;43(6):3143. PMCID: PMC4902810

Spring BQ, Bryan Sears R, Zheng LZ, Mai Z, Watanabe R, Sherwood ME, Schoenfeld DA, Pogue BW, Pereira SP, Villa E, Hasan T. A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways. Nat Nanotechnol.2016 Apr;11(4):378-87. PMCID: PMC4821671

Tangutoori S, Spring BQ, Mai Z, Palanisami A, Mensah LB, Hasan T. Simultaneous delivery of cytotoxic and biologic therapeutics using nanophotoactivatable liposomes enhances treatment efficacy in a mouse model of pancreatic cancer. Nanomedicine. 2016 Jan;12(1):223-34. PMCID: PMC4728029

Wang S, Hüttmann G, Scholzen T, Zhang Z, Vogel A, Hasan T, Rahmanzadeh R. A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67. Sci Rep. 2016 Jun 1;6:27032. PMCID: PMC4887907


Apiou-Sbirlea G, Guillermo J, Tearney J, Birngruber R, Hasan T, Anderson RR. Anatomy and Physiology of Translation: The Academic Research Imperative. Clin. Invest.(London). 2015: 5(10): 797-804.

Elliott JT, Samkoe KS, Gunn JR, Stewart EE, Gardner TB, Tichauer KM, Lee TY, Hoopes PJ, Pereira SP, Hasan T, Pogue BW. Perfusion CT Estimates Photosensitizer Uptake and Biodistribution in a Rabbit Orthotopic Pancreatic Cancer Model: A Pilot Study. Acad Radiol. 2015 May;22(5):572-9. PMCID: PMC4395543

Hempstead J, Jones DP, Ziouche A, Cramer GM, Rizvi I, Arnason S, Hasan T, Celli JP. Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models. Sci Rep. 2015 May 12;5:10093. PMCID: PMC4428052

Kim JH, Park JM, Roh YJ, Kim IW, Hasan T, Choi MG. Enhanced efficacy of photodynamic therapy by inhibiting ABCG2 in colon cancers. BMC Cancer. 2015 Jul 7;15:504. PMCID: PMC4494642

Kushibiki T, Tu Y, Abu-Yousif AO, Hasan T. Photodynamic activation as a molecular switch to promote osteoblast cell differentiation via AP-1 activation. Sci Rep. 2015 Aug 17;5:13114. PMCID: PMC4538568

Mallidi S, Spring BQ, Chang S, Vakoc B, Hasan T. Optical Imaging, Photodynamic Therapy and Optically Triggered Combination Treatments. Cancer J. 2015 May-Jun;21(3):194-205. PMCID: PMC4459538

Mallidi S, Watanabe K, Timerman D, Schoenfeld D, Hasan T. Prediction of tumor recurrence and therapy monitoring using ultrasound-guided photoacoustic imaging. Theranostics. 2015 Jan 1;5(3):289-301. PMCID: PMC4279192

Mallidi S, Mai Z, Rizvi I, Hempstead J, Arnason S, Celli J, Hasan T. In vivo evaluation of battery-operated light-emitting diode-based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints. J Biomed Opt. 2015 Apr;20(4):048003. PMCID: PMC4408448.

Spring BQ, Rizvi I, Xu N, Hasan T. The role of photodynamic therapy in overcoming cancer drug resistance. Photochem Photobiol Sci. 2015 Aug 29;14(8):1476-91. PMCID: PMC4520758

Wang S, Huettmann G, Zhang Z, Vogel A, Birngruber R, Tangutoori S, Hasan T, Rahmanzadeh R. Light-controlled delivery of monoclonal antibodies for targeted photoinactivation of Ki-67. Mol Pharm. 2015 Sep 8;12(9):3272-81.


Anand S, Rollakanti KR, Horst RL, Hasan T, Maytin EV. Combination of Oral Vitamin D3 with Photodynamic Therapy Enhances Tumor Cell Death in a Murine Model of Cutaneous Squamous Cell Carcinoma. Photochem Photobiol. 2014 Sep-Oct;90(5):1126-35. PMCID: PMC4186664

Celli JP, Rizvi I, Blanden AR, Massodi I, Glidden MD, Pogue BW, Hasan T. An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models. Sci Rep. 2014 Jan 17;4:3751. PMCID: PMC3894557

Erdem SS, Khan S, Palanisami A, Hasan T. Rapid, low-cost fluorescent assay of β-lactamase-derived antibiotic resistance and related antibiotic susceptibility. J Biomed Opt. 2014 Oct 1;19(10):105007. PMCID: PMC4193078.

Frenette M, Hatamimoslehabadi M, Bellinger-Buckley S, Laoui S, La J, Bag S, Mallidi S, Hasan T, Bouma B, Yelleswarapu C, Rochford J. Shining Light on the Dark Side of Imaging: Excited State Absorption Enhancement of a Bis-styryl BODIPY Photoacoustic Contrast Agent. J Am Chem Soc. 2014 Nov 12;136(45):15853-6. PMCID: PMC4235371.

Ghogare AA, Rizvi I, Hasan T, Greer A. "Pointsource" Delivery of a Photosensitizer Drug and Singlet Oxygen: Eradication of Glioma Cells in Vitro. Photochem Photobiol. 2014 Sep-Oct;90(5):1119-25. PMCID: PMC4198175

Hamzei N, Samkoe KS, Elliott JT, Holt RW, Gunn JR, Hasan T, Pogue BW, Tichauer KM. Comparison of Kinetic Models for Dual-Tracer Receptor Concentration Imaging in Tumors. Austin J Biomed Eng. 2014 Mar 5;1(1). PMCID: PMC4235770

Huang HC, Hasan T. The "Nano" World in Photodynamic Therapy. Austin J Nanomed Nanotechnol. 2014;2(3): 1020.

Jermyn M, Davis SC, Dehghani H, Huggett MT, Hasan T, Pereira SP, Bown SG, Pogue BW. CT contrast predicts pancreatic cancer treatment response to verteporfin-based photodynamic therapy. Phys Med Biol. 2014 Apr 21;59(8):1911-21. PMCID: PMC4229843

Kanick SC, Davis SC, Zhao Y, Hasan T, Maytin EV, Pogue BW, Chapman MS. Dual-channel red/blue fluorescence dosimetry with broadband reflectance spectroscopic correction measures protoporphyrin IX production during photodynamic therapy of actinic keratosis. J Biomed Opt. 2014 Jul;19(7):75002. PMCID: PMC4082494

Khan S, Sallum UW, Zheng X, Nau GJ, Hasan T. Rapid optical determination of β-lactamase and antibiotic activity. BMC Microbiol. 2014 Apr 4;14(1):84. PMCID: PMC4234275

Mallidi S, Anbil S, Lee S, Manstein D, Elrington S, Kositratna G, Schoenfeld D, Pogue B, Davis SJ, Hasan T. Photosensitizer fluorescence and singlet oxygen luminescence as dosimetric predictors of topical 5-aminolevulinic acid photodynamic therapy nduced clinical erythema. J Biomed Opt. 2014 Feb 1;19(2):028001. PMCID: PMC3915169

Samkoe KS, Tichauer KM, Gunn JR, Wells WA, Hasan T, Pogue BW. Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach. Cancer Res. 2014 Dec 15;74(24):7465-74. PMCID: PMC4268352

Spring BQ, Abu-Yousif AO, Palanisami A, Rizvi I, Zheng X, Mai Z, Anbil S, Sears RB, Mensah LB, Goldschmidt R, Erdem SS, Oliva E, Hasan T. Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E933-42. PMCID: PMC3956156

Spring BQ, Palanisami A, Hasan T. Microscale receiver operating characteristic analysis of micrometastasis recognition using activatable fluorescent probes indicates leukocyte imaging as a critical factor to enhance accuracy. J Biomed Opt. 2014 Jun;19(6):066006. PMCID: PMC4053439.

Tichauer KM, Deharvengt SJ, Samkoe KS, Gunn JR, Bosenberg MW, Turk MJ, Hasan T, Stan RV, Pogue BW. Tumor Endothelial Marker Imaging in Melanomas Using Dual-Tracer Fluorescence Molecular Imaging. Mol Imaging Biol. 014 Jun;16(3):372-82. PMCID: PMC4016173

Tichauer KM, Samkoe KS, Gunn JR, Kanick SC, Hoopes PJ, Barth RJ, Kaufman PA, Hasan T, Pogue BW. Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging. Nat Med. 2014 Nov;20(11):1348-1353. PMCID: PMC4224611


Anand S, Hasan T, Maytin EV. Mechanism of Differentiation-Enhanced Photodynamic Therapy for Cancer: Upregulation of Coproporphyrinogen Oxidase by C/EBP Transcription Factors. Mol Cancer Ther. 2013 Aug;12(8):1638-50. PMCID: PMC3743443

Anbil S, Rizvi I, Celli JP, Alagic N, Pogue BW, Hasan T. Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer. J Biomed Opt. 2013 Sep 1;18(9):98004. PMCID: PMC3783041

Bartusik D, Aebisher D, Ghogare A, Ghosh G, Abramova I, Hasan T, Greer A. A Fiberoptic (Photodynamic Therapy Type) Device with a Photosensitizer and Singlet Oxygen Delivery Probe Tip for Ovarian Cancer Cell Killing. Photochem Photobiol. 2013 Jul-Aug;89(4):936-41. PMCID: PMC3701729

Davis SC, Samkoe KS, Tichauer KM, Sexton KJ, Gunn JR, Deharvengt SJ, Hasan T, Pogue BW. Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9025-30. PMCID: PMC3670304

Dhar DK, Damink SW, Brindley JH, Godfrey A, Chapman MH, Sandanayake NS, Andreola F, Mazurek S, Hasan T, Malago M, Pereira SP. Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer. Cancer. 2013 Feb 1;119(3):575-85. PMCID:PMC3492546

Mir Y, Elrington SA, Hasan T. A new nanoconstruct for epidermal growth factor receptor-targeted photo-immunotherapy of ovarian cancer. Nanomedicine. 2013 Oct;9(7):1114-22. PMCID: PMC3888221

Rizvi I, Anbila S, Alagic N, Cell JP, Zheng LZ, Palanisami A, Glidden MD, Pogue BW, Hasan T. PDT Dose Parameters Impact Tumoricidal Durability and Cell Death Pathways in a 3D Ovarian Cancer Model. Photochem Photobiol. 2013 Jul-Aug;89(4):942-52. PMCID: PMC3701746

Rizvi I, Dinh TA, Yu W, Chang Y, Sherwood ME, Hasan T. Photoimmunotherapy and irradiance modulation reduce chemotherapy cycles and toxicity in a murine model for ovarian carcinomatosis: perspective and results. Isr J Chem. 2012 Sep;52(8-9):776-787. PMCID: PMC3634612

Rizvi I, Gurkan UA, Tasoglu S, Alagic N, Celli JP, Mensah LB, Mai Z, Demirci U, Hasan T. Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules. Proc Natl Acad Sci U S A. 2013 May 28;110(22):E1974-83. PMCID: PMC3670329

Samkoe KS, Bryant A, Gunn JR, Pereira SP, Hasan T, Pogue BW. Contrast enhanced-magnetic resonance imaging as a surrogate to map verteporfin delivery in photodynamic therapy. J Biomed Opt. 2013 Dec;18(12):120504. PMCID: PMC3870269

Torosean S, Flynn B, Axelsson J, Gunn J, Samkoe KS, Hasan T, Doyley MM, Pogue BW. Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagendensitywith interstitial pressure. Nanomedicine. 2013 Feb;9(2):151-8. PMCID:PMC3505807


Abu-Yousif AO, Moor AC, Zheng X, Savellano MD, Yu W, Selbo PK, Hasan T. Epidermal Growth Factor Receptor-Targeted Photosensitizer Selectively Inhibits EGFR Signaling and Induces Targeted Phototoxicity In Ovarian Cancer Cells. Cancer Lett. 2012 Aug 28;321(2):120-7. PMCID: PMC3356439

Anand S, Ortel BJ, Pereira SP, Hasan T, Maytin EV. Biomodulatory Approaches to Photodynamic Therapy for Solid Tumors. Cancer Lett. 2012 Dec 29;326(1):8-16. PMCID:PMC3459352

Glidden MD, Celli JP, Massodi I, Rizvi I, Pogue BW, Hasan T. Image-Based Quantification of Benzoporphyrin Derivative Uptake, Localization, and Photobleaching in 3D Tumor Models, for Optimization of PDT Parameters. Theranostics. 2012;2(9):827-39. PMCID: PMC3475211

Hasan T. Using cellular mechanisms to develop effective combinations of photodynamic therapy and targeted therapies. J Natl Compr Canc Netw. 2012 Oct 1;10 Suppl 2:S23-6.

Kimani S, Ghosh G, Ghogare A, Rudshteyn B, Bartusik D, Hasan T, Greer A. Synthesis and Characterization of Mono-, Di-, and Tri-Polyethylene Glycol Chlorin e6 Conjugates for the Photokilling of Human Ovarian Cancer Cells. J Org Chem.2012 Dec 7;77(23):10638-47.

Maytin EV, Honari G, Khachemoune A, Taylor CR, Ortel B, Pogue BW, Sznycer-Taub N, Hasan T. Vitamin D Combined with Aminolevulinate (ALA)-Mediated Photodynamic Therapy (PDT) for Human Psoriasis: A Proof-of-Principle Study. Isr J Chem. 2012 Sep;52(8-9):767-775. PMCID: PMC3526008

Samkoe KS, Sexton K, Tichauer KM, Hextrum SK, Pardesi O, Davis SC, O'Hara JA, Hoopes PJ, Hasan T, Pogue BW. High Vascular Delivery of EGF, but Low Receptor Binding Rate Is Observed in AsPC-1 Tumors as Compared to Normal Pancreas. Mol Imaging Biol. 2012 Aug;14(4):472-9.

Tichauer KM, Samkoe KS, Sexton KJ, Gunn JR, Hasan T, Pogue BW. Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging. J Biomed Opt. 2012 Jun;17(6):066001. PMCID: PMC3381038

Tichauer KM, Samkoe KS, Sexton KJ, Hextrum SK, Yang HH, Klubben WS, Gunn JR, Hasan T, Pogue BW. In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging. Mol Imaging Biol. 2012 Oct;14(5):584-92. PMCID:PMC3526808


Akilov OE, Wu MX, Jin Y, Zhou Z, Geskin LJ, Falo LD, Hasan T. Vaccination with photodynamic therapy-treated macrophages induces highly suppressive T-regulatory cells. Photodermatol Photoimmunol Photomed. 2011 Apr;27(2):97-107.

Anand S, Wilson C, Hasan T, Maytin EV. Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy. Cancer Res. 2011 Sep 15;71(18):6040-50. PMCID: PMC3360482

Celli JP, Solban N, Liang A, Pereira SP, Hasan T. Verteporfin-based photodynamic therapy overcomes gemcitabine insensitivity in a panel of pancreatic cancer cell lines. Lasers Surg Med. 2011 Sep;43(7):565-74. PMCID: PMC3211106

Evans CL, Abu-Yousif A, Park YJ, Klein O J, Celli JP, Rizvi I, Zhang X, Hasan T. Killing Hypoxic Cell Populations in a 3D Tumor Model with EtNBS-PDT. PLoS One. 2011 6(8):e23434. PMCID: PMC3158086

Kim KH, Park BH, Tu Y, Hasan T, Lee B, Li J, de Boer JF. Polarization-sensitive optical frequency domain imaging based on unpolarized light. Opt Express. 2011 Jan 17;19(2):552-61.

Kosaka S, Miyoshi N, Akilov OE, Hasan T, Kawana S. Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study. Lasers Surg Med. 2011 Jul;43(5):376-81.

Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue BW, Finkelstein D, Hasan T. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res. 2010 Nov 15;70(22):9319-28.

Xu F, Celli J, Rizvi I, Moon S, Hasan T, Demirci U. A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform. Biotechnol J. 2011 Feb;6(2):204-12.


Abu-Yousif AO, Hett EC, Skoczenski AM, Hasan T. The ABC's of industry: a postdoc program provides a sneak peek into industry careers. Nat Biotechnol. 2010 Jun;28(6):625-6. No abstract available.

Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T. Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model. J Biomed Opt. 2010 Sep-Oct;15(5):051603. PMCID: PMC2948043

Celli JP, Spring BQ, Rizvi I, Evans CL, Samkoe KS, Verma S, Pogue BW, Hasan T. Imaging and photodynamic therapy: mechanisms, monitoring, and optimization. Chem Rev. 2010 May 12;110(5):2795-838. Review. No abstract available. PMCID: PMC2896821

Gibbs-Strauss SL, Samkoe KS, O'Hara JA, Davis SC, Hoopes PJ, Hasan T, Pogue BW. Detecting epidermal growth factor receptor tumor activity in vivo during cetuximab therapy of murine gliomas. Acad Radiol. 2010 Jan;17(1):7-17. PMCID: PMC2790554

Gruber JD, Paliwal A, Krishnaswamy V, Ghadyani H, Jermyn M, O'Hara JA, Davis SC, Kerley-Hamilton JS, Shworak NW, Maytin EV, Hasan T, Pogue BW. System development for high frequency ultrasound-guided fluorescence quantification of skin layers. J Biomed Opt. 2010 Mar-Apr;15(2):026028. PMCID: PMC2866260

Joo C, Evans CL, Stepinac T, Hasan T, de Boer JF. Diffusive and directional intracellular dynamics measured by field-based dynamic light scattering. Opt Express. 2010 Feb 1;18(3):2858-71. PMCID: PMC2839546

Kosaka S, Yasumoto M, Akilov OE, Hasan T, Kawana S. Comparative split-face study of 5-aminolevulinic acid photodynamic therapy with intense pulsed light for photorejuvenation of Asian skin. J Dermatol. 2010 Dec;37(12):1005-10.

Latorre-Esteves E, Akilov OE, Rai P, Beverley SM, Hasan T. Monitoring the efficacy of antimicrobial photodynamic therapy in a murine model of cutaneous leishmaniasis using L. major expressing GFP. J Biophotonics. 2010 Jun;3(5-6):328-35. PMCID: PMC2876225

Pogue BW, Samkoe KS, Hextrum S, O'Hara JA, Jermyn M, Srinivasan S, Hasan T. Imaging targeted-agent binding in vivo with two probes. J Biomed Opt. 2010 May-Jun;15(3):030513. PMCID: PMC2909298

Rahmanzadeh R, Rai P, Celli JP, Rizvi I, Baron-Lühr B, Gerdes J, Hasan T. Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer. Cancer Res. 2010 Nov 15;70(22):9234-42. PMCID: PMC3057762

Rai P, Mallidi S, Zheng X, Rahmanzadeh R, Mir Y, Elrington S, Khurshid A, Hasan T. Development and applications of photo-triggered theranostic agents. Adv Drug Deliv Rev. 2010 Aug 30;62(11):1094-124. PMCID: PMC2991599

Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue BW, Finkelstein D, Hasan T. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res. 2010 Nov 15;70(22):9319-28. PMCID: PMC3057933

Sallum UW, Zheng X, Verma S, Hasan T. Rapid functional definition of extended spectrum β-lactamase activity in bacterial cultures via competitive inhibition of fluorescent substrate cleavage. Photochem Photobiol. 2010 Nov-Dec;86(6):1267-71. PMCID: PMC3118499

Samkoe KS, Chen A, Rizvi I, O'Hara JA, Hoopes PJ, Pereira SP, Hasan T, Pogue BW. Imaging tumor variation in response to photodynamic therapy in pancreatic cancer xenograft models. Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):251-9. PMCID: PMC2902770


Abu-Yousif AO, Rizvi I, Evans CL, Celli JP, Hasan T. PuraMatrix Encapsulation of Cancer Cells. J Vis Exp. 2009; (34): 1692. PMCID: PMC3152243

Akilov OE, Ustyugova IV, Zhi L, Hasan T, Wu MX. Enhanced Susceptibility to Leishmania Infection in Resistant Mice in the Absence of Immediate Early Response Gene X-1. J Immunol. 2009 Dec 15;183(12):7994-8003.

Akilov OE, Yousaf W, Lukjan SX, Verma S, Hasan T. Optimization of topical photodynamic therapy with 3,7-bis(di-n-butylamino)phenothiazin-5-ium bromide for cutaneous leishmaniasis. Lasers Surg Med. 2009 Jul;41(5):358-65.

Anand S, Honari G, Hasan T, Elson P, Maytin EV. Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo. Clin Cancer Res. 2009 May 15;15(10):3333-43. PMCID: PMC2744072

Evans CL, Rizvi I, Hasan T, de Boer JF. In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging. Opt Express. 2009 May 25;17(11):8892-906. PMCID: PMC2836890

Gibbs-Strauss S, Pogue BW, O’Hara JA, Hoopes PJ, Hasan T. Noninvasive Measurement of Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence Allows Detection of Murine Glioma in Vivo. J Biomed Optics 2009 Jan-Feb;14(1):014007. PMCID: PMC2799166

Gibbs-Strauss SL, O'Hara JA, Srinivasan S, Hoopes PJ, Hasan T, Pogue BW. Diagnostic detection of diffuse glioma tumors in vive with molecular fluorescent probe-based transmission spectroscopy. Med Phys. 2009 Mar;36(3):974-83. PMCID: PMC2736749

Krishnaswamy V, Hoopes PJ, Samkoe KS, O'Hara JA, Hasan T, Pogue BW. Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy. J Biomed Opt 2009 Jan-Feb;14(1):014004. PMCID: PMC2813673

Lee S, Vu DH, Hinds MF, Davis SJ, Liang A, Hasan T. Errata: Pulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats. J Biomed Opt 2009 Jan-Feb;14(1):019801.

Verma S, Sallum UW, Athar H, Rosenblum L, Foley JW, Hasan T. Antimicrobial Photodynamic Efficacy of Side-chain Functionalized Benzo[a]phenothiazinium Dyes. Photochem Photobiol 2009 Jan-Feb; 85(1): 111-8.

Xu P, Gullotti E, Tong L, Highley C, Errabelli D, Hasan T, Cheng J-X, Kohane D, Yeo Y. Intracellular Drug Delivery by Poly(lactic-co-glycolic Acid) Nanoparticles, revisited. Mol Pharmaceutics 2009 Jan-Feb;6(1):190-201. PMCID: PMC2653259

Zheng X, Sallum UW, Verma S, Athar H, Evans CL, Hasan T. Exploiting a bacterial drug-resistance mechanism: a light-activated construct for the destruction of MRSA. Angew Chem Int Ed Engl 2009;48(12):2148-51.

Zhong W, Celli JP, Rizvi I, Mai Z, Spring BQ, Yun SH, Hasan T. In vivo high-resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring. Br J Cancer. 2009 Dec 15;101(12):2015-22.


Casas A, Venosa GD, Vanzulli S, Perotti C, Mamome L, Rodriguez L, Simian M, Juarranz A, Pontiggia O, Hasan T, Batlle A. Decreased metastatic phenotype in cells resistant to aminolevulinic acid-photodynamic therapy. Cancer Lett 2008 Nov 28; 271(2): 342-51. PMCID: PMC2602948

Chang SK, Rizvi I, Solban N, Hasan T. In vivo Optical Molecular Imaging of Vascular Endothelial Growth Factor for Monitoring Cancer Treatment. Clinical Cancer Research 2008; 14(13): 4146-4153.

Laubach H-J, Chang SK, Lee S, Rizvi I, Zurakowski D, Davis SJ, Taylor CR, Hasan T. In-Vivo Singlet Oxygen Dosimetry of Clinical 5-Aminolevulinic Acid Photodynamic Therapy. J Biomed Optics 2008; 13(5): 050504-1-3. PMCID: PMC2994192

Lee S, Zhu L, Minhaj AM, Hinds MF, Vu DH, Rosen DI, Davis SJ, Hasan T. Pulsed diode laser-based monitor for singlet molecular oxygen. J Biomed Opt 2008 May-Jun; 13(3): 034010. PMCID: PMC2994198

Lee S, Vu DH, Hinds MF, Davis SJ, Liang A, Hasan T. Pulsed diode laser-based singlet oxygen monitor for photodynamic therapy: in vivo studies of tumor-laden rats. J Biomed Opt 2008 Nov-Dec; 13(6): 064035. PMCID: PMC2994193

Pogue BW, Sheng C, Benevides J, Forcione D, Puricelli B, Nishioka N, Hasan T. Protoporphyrin IX fluorescence photobleaching increases with the use of fractionated irradiation in the esophagus. J Biomed Optics 2008; 13(3): 034009/1-034009/10.

Styer AK, Sullivan BT, Puder M, Arsenault D, Petrozza JC, Serikawa T, Chang S, Hasan T, Gonzalez RR, Rueda BR. Ablation of leptin signaling disrupts the establishment, development and maintenance of endometriosis-like lesions in a murine model. Endocrinology 2008; 149 (2): 506-514. PMCID: PMC2219296

Waisbren SE, Bowles H, Hasan T, Zou KH, Emans SJ, Goldberg C, Gould S, Levine D, Lieberman E, Loeken M, Longtine J, Nadelson C, Patenaude AF, Quinn D, Randolph AG, Solet JM, Ullrich N, Walensky R, Weitzman P, Christou H. Gender Differences in Research Grant Applications and Funding Outcomes for Medical School Faculty. Journal of Women’s Health 2008; 17 (2): 207-214.


Akilov OE, Kosaka S, O'riordan K, Hasan T. Photodynamic therapy for cutaneous leishmaniasis: the effectiveness of topical phenothiaziniums in parasite eradication and Th1 immune response stimulation. Photochem Photobiol Sci 2007 Oct; 6(10): 1067-75.

Akilov OE, Donovan MJ, Stepinac T, Carter CR, Whitcomb JP, Hasan T, McDowell MA. T helper type 1 cytokines and keratinocyte growth factor play a critical role in pseudoepitheliomatous hyperplasia initiation during cutaneous leishmaniasis. Arch Dermatol Res 2007 Sep; 299(7): 315-25.

Akilov OE, Kosaka S, O'Riordan K, Hasan T. Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells. Exp Dermatol 2007 Aug; 16(8): 651-60.

Akilov OE, Khachemoune A, Hasan T. Clinical manifestations and classification of Old World cutaneous leishmaniasis. Int J Dermatol 2007; 46: 132-42.

Kosaka S, Akilov OE, O’Riordan K, Hasan T. A Mechanistic Study of delta-Aminolevulinic Acid-Based Photodynamic Therapy for Cutaneous Leishmaniasis. J Invest Dermatol 2007; 127(6): 1546-1549.

O'Riordan K, Akilov OE, Chang SK, Foley JW, Hasan T. Real-time fluorescence monitoring of phenothiazinium photosensitizers and their anti-mycobacterial photodynamic activity against Mycobacterium bovis BCG in in vitro and in vivo models of localized infection. Photochem Photobiol Sci 2007 Oct; 6(10): 1117-23.

Sato N, Moore BW, Keevey S, Drazba JA, Hasan T, Maytin EV. Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes. J Invest Dermatol 2007; 127(4): 925-34.

Sheng C, Hoopes PJ, Hasan T, Pogue BW. Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus. Photochem Photobiol 2007 May-Jun; 83(3): 738-48.

Zhou X, Chen B, Hoopes PJ, Hasan T, Pogue BW. Peptide-induced inflammatory increase in vascular permeability improves photosensitizer delivery and intersubject photodynamic treatment efficacy. Radiat Res 2007 Sep; 168(3): 299-307.


Akilov OE, Kosaka S, O’Riordan K, Song X, Sherwood M, Flotte TJ, Foley JW, Hasan T. The role of photosensitizer molecular charge and structure on the efficacy of photodynamic therapy against Leishmania parasites. Chem & Biol 2006; 13(8): 839-847.

Casas A, Perotti C, Ortel B, Di Venosa G, Saccoliti M, Batlle A, Hasan T. Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells. Int J Oncol 2006 Aug; 29(20): 397-405.

Chen B, Pogue BW, Luna JM, Hardman RL, Hoopes PJ, Hasan T. Tumor vascular permeabilization by vascular-targeting photosensitization: effects, mechanism and therapeutic implications. Clin Cancer Res 2006; 12(3): 917-23.

Gibbs SL, Chen B, O'Hara JA, Hoopes PJ, Hasan T, Pogue BW. Protoporphyrin IX Level Correlates with Number of Mitochondria, but Increases in Production Correlate with Tumor Cell Size. Photochem Photobiol 2006 Sep-Oct;82(5):1334-41.

Kosaka S, Kawana Seiji, Zouboulis C, Hasan T, Ortel B. Targeting of sebocytes by aminolevulinic acid-dependent photosensitization. Photochem Photobiol 2006; 82(2): 453-7.

Kosharskyy B, Solban N, Chang SK, Rizvi I, Chang Y, Hasan T. A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer. Cancer Res 2006 Nov 15; 66(22): 10953-8.

O’Riordan K, Sharlin DS, Gross J, Chang S, Errabelli D, Akilov OE, Kosaka S, Nau GJ, Hasan T. Photoinactivation of mycobacteria in vitro and in a new murine model of localized mycobacterium bovis BCG-induced granulomatous infection. Antimicrob Agents Chemother 2006; 50(5): 1828-34. PMCID: PMC1472192

Sinha AK, Anand S, Ortel BJ, Chang Y, Mai Z, Hasan T, Maytin EV. Methotrexate used in combination with aminolevulinic acid for photodynamic killing of prostate cancer cells. Brit J Cancer 2006 Aug 21; 95: 485-495.

Solban N, Rizvi I, Hasan T. Targeted photodynamic therapy. Lasers Surg Med 2006 Jun; 38(5): 522-31.

Solban N, Selbo PK, Sinha AK, Chang SK, Hasan T. Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer. Cancer Res 2006 Jun 1; 66(11): 5633-40.

Yelin D, Rizvi I, White WM, Motz JT, Hasan T, Bouma BE, Tearney GJ. Three-dimensional miniature endoscopy. Nature 2006; Oct 443: 19.

Zhou X, Chen B, Hoopes PJ, Hasan T, Pogue BW. Tumor vascular area correlates with photosensitizer uptake; analysis of verteporfin microvascular delivery in the dunning rat prostate tumor. Photochem Photobiol 2006 Sep-Oct; 82(5): 1348-57.

Zhou X, Pogue BW, Chen B, Demidenko E, Joshi R, Hoopes J, Hasan T. Pretreatment photosensitizer dosimetry reduces variation in tumor response. Intl J of Rad Onc 2006; 64(4): 1211-20.


Chen B, Pogue BW, Zhou X, O’Hara JA, Solban N, Demidenko E, Hoopes PJ, Hasan T. Effect of tumor host microenvironment on photodynamic therapy in a rat prostate tumor model. Clin Cancer Res 2005;11(2): 720-7.

Chen B, Pogue BW, Hoopes PJ, Hasan T. Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy. Int J Radiat Oncol Biol Phys 2005; 61 (4): 1216-26.

Del Carmen MG, Rizvi I, Chang Y, Moor AC, Oliva E, Sherwood M, Pogue B, Hasan T. Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivo. J Natl Cancer Inst 2005; 97(20): 1516-24.

Lambrechts SA, Demidova TN, Aalders MC, Hasan T, Hamblin MR. Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice. Photochem Photobiol 2005; 4: 503-9. PMCID: PMC3071043

Savellano M, Hasan T. Photochemical targeting of epidermal growth factor receptor: a mechanistic study. Clin Cancer Res 2005; 11(4): 1658-68.


Gad F, Zahra T, Khan Z, Hasan T, Hamblin MR. Effects of growth phase and extracellular slime on photodynamic inactivation of gram-positive pathogenic bacteria. Antimicrob Agents Chemother 2004; 48(6): 2173-8. PMCID: PMC415578

Gad F, Zahra T, Francis K, Hasan T, Hamblin MR. Targeted photodynamic therapy of established soft tissue in mice. Photochem Photobiol Sci 2004; 3(5): 451-8. PMCID: PMC3071693

Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP. In vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res 2004; 64(15): 5044-7.

Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci. 2004 May; 3(5): 436–450. PMCID: PMC3071049

Zhou X, Pogue BW, Chen B, Hasan, T. Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors. Photochem Photobiol 2004; 79(4): 323-31.


Chen B, Pogue BW, Goodwin IA, O'Hara JA, Wilmot CM, Hutchins JE, Hoopes PJ, Hasan T. Blood flow dynamics following photodynamic therapy with verteporfin in the RIF-1 tumor. Radiat Res 2003 Oct; 160(4): 452-9.

Hamblin MR, Miller JL, Rizvi I, Loew HG, Hasan T. Pegylation of charged polymer-photosensitizer conjugates: effects on photodynamic efficacy. Br J Cancer 2003; 89(5): 937-43.

Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T. Optical monitoring and treatment of potentially lethal wound infections in vivo. J Infect Dis 2003; 187(11): 1717-25.

Jung K, Krell HW, Ortel B, Hasan T, Romer A, Schnorr D, Loening SA, Lein M. Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats. Prostate 2003; 54(3):206-11.

Pogue BW, O’Hara JA, Demidenko E, Wilmot CM, Goodwin IA, Chen B, Swartz HM, Hasan T. Photodynamic therapy with verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced radiation sensitivity. Cancer Res 2003; 63(5): 1025-33.

Savellano M, Hasan T. Targeting cells that overexpress the epidermal growth factor receptor with polyethylene glycolated BPD verteporfin photosensitizer immunoconjugates. Photochem Photobiol 2003; 77(4): 431-9.


Duska LR, Wimberly J, Deutsch TF, Ortel B, Haas J, Houck K, Hasan T. Detection of female lower genital tract dysplasia using orally administered aminolevulinic acid induced protoporphyrin IX: a preliminary study. Gynecol Oncol 2002; 85(1):125-8.

Haimovici R, Ciulla T, Miller J, Hasan T, Flotte T, Kenney AG, Schomacker KT, T, Gragoudas ES. Localization of rose bengal, aluminum phthalocyanine tetrasulfonate, and chlorin E6 in the rabbit eye. Retina 2002; 22(1):65-74.

Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol 2002; 75(1):51-57.

Hamblin MR, O’Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, Hasan T. Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria. J Antimicrob Chemother 2002; 49(6):941-51.

Ortel B, Sharlin D, O’Donnell D, Sinha AK, Maytin EV, Hasan T. Differentation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells. Br J Cancer 2002; 87(11):1321-7.

Sullivan LG, Hasan T, Wright M, Mankin HJ, Towle CA. Photodynamic treatment has chondroprotective effects on articular cartilage. J Orthop Res 2002; 20(2):241-8.


Heitner T, Moor A, Garrison JL, Marks C, Hasan T, Marks JD. Selection of cell binding and internalizing epidermal growth factor receptor antibodies from a phage display library. J Immunol Methods 2001; 248:17-30.

Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T. Pegylation of a chlorine6 polymer conjugate increases tumor targeting of photosensitizer. Cancer Res 2001; 61:7155-7162.

Pogue BW, Ortel B, Chen N, Redmond RW, Hasan T. A photobiological and photophysical-based study of phototoxicity of two chlorins. Cancer Res 2001; 61:717-724.

Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T. Epidermal growth factor receptor-targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in-vivo. Cancer Res 2001; 61:4490-4496.

Sullivan LG, Hasan T, Wright M, Mankin HJ, Towle CA. Photodynamic treatment has chondroprotective effects on articular cartilage. J Orthop Res 2001; 221:1-8.


Del Governatore M, Hamblin MR, Piccinini EE, Ugolini G, Hasan T. Targeted photodestruction of human colon cancer cells using charged 17.1a chlorine6 immunoconjugates. Br J Cancer 2000; 82:56-64.

Del Governatore M, Hamblin MR, Shea CR, Rizvi I, Molpus KL, Tanabe KK, Hasan T. Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorine6 immunoconjugate. Cancer Res 2000; 60:4200-4205.

Hamblin MR, Del Governatore M, Rizvi I, Hasan T. Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer. Br J Cancer 2000; 83:1544-1551.

Lein M, Jung K, Le D, Hasan T, Ortel B, Bochert D, Giessing M, Schnorr D, Loening S. Synthetic inhibitor of matrix metalloproteinases (Batimastat) reduce prostate cancer growth in a orthotopic rat model. Prostate 2000; 43(2):77-82.

Lein M, Ortel B, Koenig F, Misdraji J, McDougal WS, Jung K, Loening SA, Hasan T. Laser-induced hyperthermia in rat prostate cancer: role of site of tumor implantation. J Urol 2000; 56:167-172.

Molpus KL, Hamblin MR, Rizvi I, Hasan T. Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates. Gynecol Oncol 2000; 76:397-404.

Schmidt U, Hasan T. Mechanisms of action of photodynamic therapy with verteporfin for the treatment of age-related macular degradation. Surv Ophthalmol 2000; 45:195-214.