Laser vaccine adjuvant effects

A laser-based vaccine adjuvant is expected to sufficiently boost both humoral and cellular immune responses with few side effects due to its local application. 

We are developing a new laser system that can be convenient to apply and unlimitedly re-usable in the clinic.  With this new laser instrument, we can reduce a dose and thus the expense of an existing vaccine, or we can induce a stronger immune response in relatively immune-compromised populations such as the elderly and infants.

Projects

• Suppression of Th17 differentiation by IEX-1
• IEX-1 can be a potential target for prevention of colitis and colon cancer
• Hypertension onset independent of inflammation
• Laser vaccine adjuvant effects
• A complex interaction between Gαi2 and Gαi3
• A linkage of Gαi2 and TGF-β signaling via a newly discovered Smad phosphatase