2019

Kwok SJJ, Forward S, Wertheimer CM, Liapis AC, Lin HH, Kim M, Seiler TG, Birngruber R, Kochevar IE, Seiler T, Yun SH. Selective Equatorial Sclera Crosslinking in the Orbit Using a Metal-Coated Polymer Waveguide. Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2563-2570. PMCID: PMC6586079

Redmond RW, Kochevar IE. Medical Applications of Rose Bengal- and Riboflavin-Photosensitized Protein Crosslinking. Photochem Photobiol. 2019 Sep;95(5):1097-1115. Review.

Wertheimer CM, Elhardt C, Kaminsky SM, Pham L, Pei Q, Mendes B, Afshar S, Kochevar IE. Enhancing Rose Bengal-Photosensitized Protein Crosslinking in the Cornea. Invest Ophthalmol Vis Sci. 2019 May 1;60(6):1845-1852.

2018

Lorenzo-Martín E, Gallego-Muñoz P, Ibares-Frías L, Marcos S, Pérez-Merino P, Fernández I, Kochevar IE, Martínez-García MC. Rose Bengal and Green Light Versus Riboflavin-UVA Cross-Linking: Corneal Wound Repair Response. Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4821-4830.

Soeken TA, Zhu H, DeMartelaere S, Davies BW, Kim M, Wang HC, Aden J, Grimm R, Alt C, Kochevar IE, Johnson AJ. Sealing of Corneal Lacerations Using Photoactivated Rose Bengal Dye and Amniotic Membrane. Cornea. 2018 Feb;37(2):211-217.

2017

Alarcon EI, Poblete H, Roh H, Couture JF, Comer J, Kochevar IE. Rose Bengal Binding to Collagen and Tissue Photobonding. ACS Omega. 2017 Oct 11;2(10):6646-6657. PMCID: PMC6644953

Bekesi N, Gallego-Muñoz P, Ibarés-Frías L, Perez-Merino P, Martinez-Garcia MC, Kochevar IE, Marcos S. Biomechanical Changes After In Vivo Collagen Cross-Linking With Rose Bengal-Green Light and Riboflavin-UVA. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1612-1620.

Gallego-Muñoz P, Ibares-Frías L, Lorenzo E, Marcos S, Peréz-Merino P, Bekesi N, Kochevar IE, Martínez-García MC. Corneal Wound Repair After Rose Bengal and Green Light Crosslinking: Clinical and Histologic Study. Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3471-3480.

Kwok SJJ, Kim M, Lin HH, Seiler TG, Beck E, Shao P, Kochevar IE, Seiler T, Yun SH. Flexible Optical Waveguides for Uniform Periscleral Cross-Linking. Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2596-2602. PMCID: PMC5433838

Ortega-Martinez A, Touchette G, Zhu H, Kochevar IE, Franco W. Variations in the endogenous fluorescence of rabbit corneas after mechanical property alterations. J Biomed Opt. 2017 Sep;22(9):1-7.

Pupkaite J, Ahumada M, Mclaughlin S, Temkit M, Alaziz S, Seymour R, Ruel M, Kochevar I, Griffith M, Suuronen EJ, Alarcon EI. Collagen-Based Photoactive Agent for Tissue Bonding. ACS Appl Mater Interfaces. 2017 Mar 22;9(11):9265-9270.

Senthil-Kumar P, Ng-Glazier JH, Randolph MA, Bodugoz-Senturk H, Muratoglu OK, Kochevar IE, Winograd JM, Redmond RW. An intraluminal stent facilitates light-activated vascular anastomosis. J Trauma Acute Care Surg. 2017 Jul;83(1 Suppl 1):S43-S49.

Seiler TG, Engler M, Beck E, Birngruber R, Kochevar IE. Interface Bonding With Corneal Crosslinking (CXL) After LASIK Ex Vivo. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6292-6298.

Zhu H, Kochevar IE, Behlau I, Zhao J, Wang F, Wang Y, Sun X, Hamblin MR, Dai T. Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):586-593. PMCID: PMC5283079

2016

Bekesi N, Kochevar IE, Marcos S. Corneal Biomechanical Response Following Collagen Cross-Linking With Rose Bengal-Green Light and Riboflavin-UVA. Invest Ophthalmol Vis Sci. 2016 Mar 1;57(3):992-1001.

Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 Jul;32(6):421-30.

Fairbairn NG, Ng-Glazier J, Meppelink AM, Randolph MA, Valerio IL, Fleming ME, Kochevar IE, Winograd JM, Redmond RW. Erratum: Light-Activated Sealing of Acellular Nerve Allografts following Nerve Gap Injury. J Reconstr Microsurg. 2016 Nov;32(9):e1. No abstract available.

Kochevar IE, Redmond RW. Light-activated wound healing and tissue modification. Biochemist. 2016 Dec;38(6):20-3.

Liu C, Vojnovic D, Kochevar IE, Jurkunas UV. UV-A Irradiation Activates Nrf2-Regulated Antioxidant Defense and Induces p53/Caspase3-Dependent Apoptosis in Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2319-27. PMCID: PMC4855825

Senthil-Kumar P, Ni T, Randolph MA, Velmahos GC, Kochevar IE, Redmond RW. A light-activated amnion wrap strengthens colonic anastomosis and reduces peri-anastomotic adhesions. Lasers Surg Med. 2016 Jul;48(5):530-7.

Zhu H, Alt C, Webb RH, Melki S, Kochevar IE. Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation. Cornea. 2016 Sep;35(9):1234-41.

Zhu H, Kochevar IE, Behlau I, Zhao J, Wang F, Wang Y, Sun X, Hamblin MR, Dai T. Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):586-593. PMCID: PMC5283079

2015

Marcos S, Alejandre N, Lamela J, Dorronsoro C, Kochevar IE. Toward New Engagement Paradigms For Intraocular Lenses: Light-Initiated Bonding of Capsular Bag to Lens Materials. Invest Ophthalmol Vis Sci. 2015 Jul 1;56(8):4249-56.

Xu N, Yao M, Farinelli W, Hajjarian Z, Wang Y, Redmond RW, Kochevar IE. Light-activated sealing of skin wounds. Lasers Surg Med. 2015 Jan;47(1):17-29.

2014

Liu C, Chen Y, Kochevar IE, Jurkunas UV. Decreased DJ-1 Leads to Impaired Nrf2-Regulated Antioxidant Defense and Increased UV-A-Induced Apoptosis in Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2014 Jul 31;55(9):5551-60. PMCID: PMC4160071

Yao M, Gu C, Doyle FJ Jr, Zhu H, Redmond RW, Kochevar IE. Why is Rose Bengal More Phototoxic to Fibroblasts In Vitro Than In Vivo? Photochem Photobiol. 2014 Mar;90(2):297-305.

2013

Cherfan D, Verter EE, Melki S, Gisel TE, Doyle FJ Jr, Scarcelli G, Yun SH, Redmond RW, Kochevar IE. Collagen cross-linking using rose bengal and green light to increase corneal stiffness. Invest Ophthalmol Vis Sci. 2013 May 13;54(5):3426-33.

2012

Ni T, Senthil-Kumar P, Dubbin K, Aznar-Cervantes SD, Datta N, Randolph MA, Cenis JL, Rutledge GC, Kochevar IE, Redmond RW. A photoactivated nanofiber graft material for augmented achilles tendon repair. Lasers Surg Med. 2012 Oct;44(8):645-52.

Yang P, Yao M, Demartelaere SL, Redmond RW, Kochevar IE. Light-activated sutureless closure of wounds in thin skin. Lasers Surg Med. 2012 Feb;44(2):163-7.

2011

Franco RA, Dowdall JR, Bujold K, Amann C, Faquin W, Redmond RW, Kochevar IE. Photochemical repair of vocal fold microflap defects. Laryngoscope. 2011 Jun;121(6):1244-51.

Gu C, Ni T, Verter EE, Redmond RW, Kochevar IE, Yao M. Photochemical tissue bonding: a potential strategy for treating limbal stem cell deficiency. Lasers Surg Med. 2011 Jul;43(5):433-42.

Verter EE, Gisel TE, Yang P, Johnson AJ, Redmond RW, Kochevar IE. Light-initiated bonding of amniotic membrane to cornea. Invest Ophthalmol Vis Sci. 2011 Dec 9;52(13):9470-7.

Wang Y, Kochevar IE, Redmond RW, Yao M. A light-activated method for repair of corneal surface defects. Lasers Surg Med. 2011 Aug;43(6):481-9.

2010

Yao M, Yaroslavsky A, Henry FP, Redmond RW, Kochevar IE. Phototoxicity is not associated with photochemical tissue bonding of skin. Lasers Surg Med. 2010 Feb;42(2):123-31.

2009

Choi WS, Mitsumoto A, Kochevar IE. Involvement of reactive oxygen species in TGF-beta1-induced tropoelastin expression by human dermal fibroblasts. Photochem Photobiol. 2009 Nov-Dec;85(6):1425-33.

Henry FP, Côté D, Randolph MA, Rust EA, Redmond RW, Kochevar IE, Lin CP, Winograd JM. Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg 2009 Feb;123(2 Suppl):123S-30S.

Henry FP, Goyal NA, David WS, Wes D, Bujold KE, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Improving electrophysiologic and histologic outcomes by photochemically sealing amnion to the peripheral nerve repair site. Surgery 2009 Mar;145(3):313-21.

Ibusuki S, Papadopoulos A, Ranka MP, Halbesma GJ, Randolph MA, Redmond RW, Kochevar IE, Gill TJ. Engineering cartilage in a photochemically crosslinked collagen gel. J Knee Surg 2009 Jan;22(1):72-81.

O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Photochemical sealing improves outcome following peripheral neurorrhaphy. J Surg Res 2009 Jan;151(1):33-9.

O'Neill AC, Randolph MA, Bujold KE, Kochevar IE, Redmond RW, Winograd JM. Preparation and integration of human amnion nerve conduits using a light-activated technique. Plast Reconstr Surg. 2009 Aug;124(2):428-37.

Yamaura M, Yao M, Yaroslavsky I, Cohen R, Smotrich M, Kochevar IE. Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes. Lasers Surg Med. 2009 Apr;41(4):282-90.

2008

Valencia A, Kochevar IE. Nox1-based NADPH oxidase is the major source of UVA-induced reactive oxygen species in human keratinocytes. J Invest Dermatol 2008;128(1):214-22.

2007

Ibusuki S, Halbesma GJ, Randolph MA, Redmond RW, Kochevar IE, Gill TJ. Photochemically cross-linked collagen gels as three-dimensional scaffolds for tissue engineering. Tissue Eng 2007;13(8):1995-2001.

Johnson TS, O’Neill AC, Motarjem P, Amman C, Zeballos JL, Bujold KE, Nguyen T, Randolph MA, Winograd JM, Kochevar IE, Redmond RW. Photochemical tissue bonding: A novel technique in peripheral nerve repair. J Surg Res 2007;143(2):224-9.

O'Neill AC, Winograd JM, Zeballos JL, Johnson TS, Randolph MA, Bujold KE, Kochevar IE, Redmond RW. Microvascular anastomosis using a photochemical tissue bonding technique. Laser Surg Med 2007;39(9):716-722.

2006

Redmond RW, Kochevar IE. Spatially-Resolved Cellular Responses to Singlet Oxygen. Photochem Photobiol 2006; 82(5):1178-1186.

Valencia A, Kochevar IE. Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome. Free Radical Bio Med 2006 Feb;40(4):641-50.

Valencia A, Rajadurai A, Carle AB, Kochevar IE. 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: Roles of NADPH oxidase, mitochondria, and lipid rafts. Free Radic Bio Med 2006;41(11):1704-18. PMCID: PMC1880892

2005

Chan BP, Amann C, Yaroslavsky AN, Title C, Smink D, Zarins B, Kochevar IE, Redmond RW. Photochemical repair of Achilles tendon rupture in a rat model. J Surg Res 2005;124(2):274-9.

Kamegaya Y, Farinelli WA, Vila Echague AV, Akita H, Gallagher J, Flotte TJ, Anderson RR, Redmond RW, Kochevar IE. Evaluation of photochemical tissue bonding for closure of skin incisions and excisions. Laser Surg Med 2005;37(4):264-70.

Wang H, Kochevar IE. Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes. Free Radic Bio Med 2005;38(7):890-7.

2004

Kossodo S, Wong W-R, Simon G, Kochevar IE. Effects of UVR and UVR-induced cytokines on production of extracellular matrix proteins and proteases by dermal fibroblasts cultured in collagen gels. Photochem Photobiol 2004;79(1):86-93.

Proano CE, Azar DT, Mocan MC, Redmond RW, Kochevar IE. Photochemical keratodesmos as an adjunct to sutures for bonding penetrating keratoplasty corneal incisions. J Cataract Refract Surg 2004;30:2420-4.

Proano CE, Mulroy L, Jones E, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for bonding corneal incisions. Invest Ophthalmol Vis Sci 2004;45(7):2177-81.

2003

Nguyen B, Kochevar IE. Influence of hydration on dihydroxyacetone-induced pigmentation of stratum corneum. J Invest Dermatol 2003; 120:665-661.

Nguyen B, Kochevar IE. Factors influencing sunless tanning with dihydroxyacetone. Br J Dermatol 2003; 149:332-340.

Zhuang S, Ouedraogo GD, Kochevar IE. Down-regulation of epidermal growth factor receptor Signaling by singlet oxygen through activation of caspase-3 and protein phosphatases. Oncogene 2003; 22:4413-4424.

Zhuang S, Kochevar IE. Ultraviolet A radiation induces rapid apoptosis of human leukemia cells by Fas ligand-independent activation of the Fas death pathway. Photochem Photobiol 2003; 78:61-67.

Zhuang S, Kochevar IE. Singlet oxygen-induced activation of Akt/Protein Kinase B is independent of growth factor receptors. Photochem Photobiol 2003; 78:361-371.

2002

Chan BP, Kochevar IE, Redmond RW. Enhancement of porcine skin graft adherence using a light-activated process. J Surg Res 2002; 108:77-84.

2001

Zhuang S, Demirs JT, Kochevar IE. Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation. Oncogene 2001; 20:6764-6776.

2000

Kochevar IE, Lynch MC, Zhuang S, Lambert CR. Singlet oxygen, but not oxidizing radicals, induces apoptosis in HL-60 cells. Photochem Photobiol 2000; 72:548-553.

Lin CP, Lynch MA, Kochevar IE. Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells. Exp Cell Res 2000; 259:351-359.

Mulroy L, Kim J, Wu I, Sharper P, Melki S, Azar DT, Redmond RW, Kochevar IE. Photochemical keratodesmos for repair of lamellar corneal incisions. Invest Ophth Vis Sci 2000; 41:3335-3340.

Tartier L, McCarey YL, Biaglow JE, Kochevar IE, Held KD. Apoptosis induced by dithiothreitol in HL-60 cells shows activation of caspase-3 and is independent of mitochondria. Cell Death Differen 2000; 7:1002-1010.

Zhuang S, Demirs JT, Kochevar IE. P38 mitogen-activated protein kinase mediates Bid cleavage, mitochondria dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem 2000; 275:25939-25948.